Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558566 | 0.85 | NFKB1 (0.44) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL5780605 | 0.81 | — | — | |
| SCHEMBL11648463 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL6009969 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL20870669 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL145522 | 0.74 | — | — | |
| SCHEMBL1201195 | 0.74 | — | — | |
| SCHEMBL10347941 | 0.74 | — | — | |
| SCHEMBL10507947 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL7536003 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167444-A1 | Abc Transporter Inhibitor | SUNTORY LIMITED (JP) | 2008-07-10 | — | — | US | disclosed |
| EP-1721901-A1 | ABC TRANSPORTER INHIBITOR | SUNTORY LIMITED (JP) | 2006-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167444-A1 | Abc Transporter Inhibitor | SLC47A1, ABCC1, SLC47A2 | ALDH1A1 2914/4885LMNA 3055/4885HSD17B10 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.