SCHEMBL488024

SCHEMBL488024

Cc1cncc([N+](=O)[O-])c1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.58
ACHE P22303 2/20 0.50
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
HCAR2 Q8TDS4 1/20 0.41
CYP3A4 P08684 2/20 0.39
CYP19A1 P11511 1/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL28151318 0.86 TSHR (0.44) TSHRACHEHSD17B10HCAR2HTT
SCHEMBL5252228 0.84 CYP19A1 (0.55) TSHRALDH1A1CYP3A4CYP19A1LMNA
SCHEMBL2074168 0.80 TSHR (0.50) TSHRACHEHSD17B10ALDH1A1TDP1
Ethylene SCHEMBL28777120 0.79 CYP19A1 (0.50) TSHRALDH1A1CYP3A4CYP19A1LMNA
SCHEMBL17873457 0.74 HCAR2 (0.41) TSHRALDH1A1TDP1HCAR2CYP19A1
SCHEMBL3607175 0.74 LMNA (0.42) TSHRALDH1A1CYP19A1LMNAHTT
SCHEMBL826834 0.74 ALDH1A1 (0.50) TSHRHSD17B10ALDH1A1TDP1HCAR2
SCHEMBL2167915 0.74 ALDH1A1 (0.50) TSHRHSD17B10ALDH1A1TDP1CYP19A1
SCHEMBL529746 0.74 MAPT (0.50) TSHRALDH1A1HCAR2CYP3A4CYP19A1
SCHEMBL7666882 0.74 CYP19A1 (0.39) TSHRALDH1A1CYP3A4CYP19A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119486728-A Proteolysis targeting chimeric of mucosa-associated lymphoid tissue lymphoma translocation protein 1 特吉德治疗公司 2025-02-18 CN disclosed
US-20230225201-A1 Organic Light Emitting Diode and Device Comprising the Same NOVALED GMBH (DE) 2023-07-13 US disclosed
WO-2022073425-A1 SMALL MOLECULE COMPOUND SERVING AS JAK KINASE INHIBITOR, AND USE THEREOF 嘉兴特科罗生物科技有限公司 2022-04-14 WO disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
CN-103396359-B Iminipyridine derivatives and they purposes as microbicide 先正达参股股份有限公司 2016-06-29 CN disclosed
WO-2016049586-A2 NON-BETA LACTAM ANTIBIOTICS UNIVERSITY OF NOTRE DAME DU LAC (US) 2016-03-31 WO disclosed
EP-2049488-B1 N'-CYANO-N-ALKYL HALIDE IMIDE AMIDE DERIVATIVES BAYER IP GMBH (DE) 2015-12-09 EP disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
CN-101460502-A Bicyclic enamino(thio)carbonyl compounds BAYER CROPSCIENCE AG (DE) 2009-06-17 CN disclosed
CN-101454316-A Substituted enaminocarbonyl compounds for use as pesticides BAYER CROPSCIENCE AG (DE) 2009-06-10 CN disclosed
US-7528140-B2 Substituted pyrrolo[3,2-d]pyrimidines as glycogen synthase kinase (GSK) inhibitors TEIJIN LIMITED (JP) 2009-05-05 US disclosed
US-7528140-B2 Substituted pyrrolo[3,2-d]pyrimidines as glycogen synthase kinase (GSK) inhibitors TEIJIN LIMITED (JP) 2009-05-05 US disclosed
CN-101415682-A Substituted enaminocarbonyl compounds BAYER CROPSCIENCE AG (DE) 2009-04-22 CN disclosed
WO-2002090328-A1 THE PREPARATION OF SUBSTITUTED PYRIDINES UTILIZING NITRIC AND AN ANHYDRIDE REILLY INDUSTRIES, INC. (US) 2002-11-14 WO disclosed
US-6476021-B1 Compounds having cGMP-PDE inhibitory effect MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2002-11-05 US disclosed
CN-1090189-C pyrazolopyrimidines JANSSEN PHARMACEUTICA NV (BE) 2002-09-04 CN disclosed
EP-1048666-A1 NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 EP disclosed
CN-1205009-A Pyrazolopyrimidines type compound JANSSEN PHARMACEUTICA NV (BE) 1999-01-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 TSHR 507/4885ACHE 710/4885HSD17B10 1036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.