SCHEMBL488050

SCHEMBL488050

CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCS)OC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.76

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.76
LPAR3 Q9UBY5 7/20 0.72
LPAR1 Q92633 4/20 0.72
ENPP2 Q13822 7/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
LPAR2 Q9HBW0 2/20 0.66
ALDH1A1 P00352 1/20 0.64
LMNA P02545 1/20 0.64
SMPD1 P17405 1/20 0.63
SELP P16109 1/20 0.60
PLCG2 P16885 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30503997 0.99 FABP3 (0.78) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL15386588 0.91 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL12236914 0.91 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL10033710 0.91 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL8738898 0.91 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL12648548 0.91 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL19821350 0.91 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL15120601 0.91 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL14793212 0.91 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL14793208 0.91 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130183270-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. (US) 2013-07-18 US claimed
EP-2410991-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (an Ohio Corporation ) (US) 2012-02-01 EP claimed
WO-2010111271-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (AN OHIO CORPORATION) (US) 2010-09-30 WO claimed
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-04-01 US claimed
US-10751418-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2020-08-25 US disclosed
US-10577554-B2 Gas-filled stabilized particles and methods of use CHILDREN'S MEDICAL CENTER CORPORATION (US) 2020-03-03 US disclosed
US-20160030596-A1 GAS-FILLED STABILIZED PARTICLES AND METHODS OF USE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2016-02-04 US disclosed
US-20160030596-A1 GAS-FILLED STABILIZED PARTICLES AND METHODS OF USE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2016-02-04 US disclosed
US-20130183270-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. (US) 2013-07-18 US disclosed
US-20130183270-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. (US) 2013-07-18 US disclosed
EP-2410991-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (an Ohio Corporation ) (US) 2012-02-01 EP disclosed
WO-2010111271-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (AN OHIO CORPORATION) (US) 2010-09-30 WO disclosed
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs FABP2, FABP1, LIPC FABP3 7/4885LPAR3 1320/4885LPAR1 896/4885
US-20130183270-A1 Orally Bioavailable Lipid-Based Constructs FABP2, FABP1, LIPC FABP3 7/4885LPAR3 1320/4885LPAR1 896/4885
US-20160030596-A1 GAS-FILLED STABILIZED PARTICLES AND METHODS OF USE LIPA, PPARG, LPXN FABP3 804/4885LPAR3 755/4885LPAR1 442/4885
US-10577554-B2 Gas-filled stabilized particles and methods of use LIPA, PPARG, LPXN FABP3 804/4885LPAR3 755/4885LPAR1 442/4885
US-10751418-B2 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 FABP3 5/4885LPAR3 1396/4885LPAR1 965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.