SCHEMBL8738898

SCHEMBL8738898

CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCC)OC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.80

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.80
LPAR3 Q9UBY5 7/20 0.77
LPAR1 Q92633 4/20 0.77
ENPP2 Q13822 7/20 0.76
SMN1; SMN2 Q16637 1/20 0.76
LPAR2 Q9HBW0 2/20 0.70
ALDH1A1 P00352 1/20 0.69
LMNA P02545 1/20 0.69
SMPD1 P17405 1/20 0.67
SELP P16109 1/20 0.64
PLCG2 P16885 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14793212 1.00 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL10033710 1.00 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL14793208 1.00 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL15386588 1.00 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL15120601 1.00 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL12236914 1.00 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL12648548 1.00 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL15386586 0.99 FABP3 (0.78) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL19821350 0.95 FABP3 (0.80) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL17232172 0.95 LPAR3 (0.85) FABP3LPAR3LPAR1ENPP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10815248-B2 Labeled chemically reactive and biologically active conjugates, and methods and compositions thereof SUN YI (US) 2020-10-27 US disclosed
US-20120128595-A1 PREPARATION OF A LIPID BLEND AND A PHOSPHOLIPID SUSPENSION CONTAINING THE LIPID BLEND LANTHEUS MEDICAL IMAGING, INC. (US) 2012-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120128595-A1 PREPARATION OF A LIPID BLEND AND A PHOSPHOLIPID SUSPENSION CONTAINING THE LIPID BLEND PHOSPHO1, PLTP, APOB FABP3 21/4885LPAR3 40/4885LPAR1 43/4885
US-10815248-B2 Labeled chemically reactive and biologically active conjugates, and methods and compositions thereof GUSB, PAICS, CD44 FABP3 1021/4885LPAR3 1029/4885LPAR1 1722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.