Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 3/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14021731 | 0.93 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2L3MBTL1ATM | |
| SCHEMBL4849425 | 0.85 | SMN1; SMN2 (0.43) | ALDH1A1MAPTSMN1; SMN2L3MBTL1ATM | |
| SCHEMBL4889143 | 0.84 | CYSLTR1 (0.47) | ALDH1A1MAPTSMN1; SMN2L3MBTL1ATM | |
| SCHEMBL4856376 | 0.84 | CYSLTR1 (0.50) | PTGDR2CYSLTR2CYSLTR1 | |
| SCHEMBL4850014 | 0.84 | SMN1; SMN2 (0.41) | ALDH1A1MAPTSMN1; SMN2L3MBTL1ATM | |
| SCHEMBL4845162 | 0.82 | NOTUM (0.42) | ALDH1A1MAPTSMN1; SMN2L3MBTL1ATM | |
| SCHEMBL4843095 | 0.82 | MAPT (0.43) | ALDH1A1MAPTSMN1; SMN2L3MBTL1ATM | |
| SCHEMBL4841922 | 0.82 | CYSLTR1 (0.47) | ALDH1A1MAPTSMN1; SMN2L3MBTL1ATM | |
| SCHEMBL4843277 | 0.80 | NOTUM (0.41) | ALDH1A1MAPTSMN1; SMN2L3MBTL1ATM | |
| SCHEMBL5726739 | 0.80 | CYSLTR1 (0.47) | MAPTPTGDR2NOTUMHDAC6CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-6635655-B1 | Agonists or antagonists of peroxisome proliferator-activated receptors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-10-21 | — | — | US | disclosed |