Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1267203 | 0.99 | TKT (0.49) | TKT | |
| SCHEMBL30758706 | 0.81 | TKT (0.51) | TKT | |
| SCHEMBL261033 | 0.81 | TKT (0.51) | TKT | |
| Hydrochloric Acid SCHEMBL29404983 | 0.81 | TKT (0.50) | TKT | |
| Hydrochloric Acid SCHEMBL9000282 | 0.80 | TKT (0.49) | TKT | |
| Bromide SCHEMBL29044448 | 0.74 | TKT (0.46) | TKT | |
| Quinoline SCHEMBL27627708 | 0.74 | TKT (0.42) | TKT | |
| SCHEMBL4252730 | 0.72 | ALDH1A1 (0.43) | — | |
| Bromide SCHEMBL7626002 | 0.70 | ALDH1A1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL16697601 | 0.68 | TKT (0.40) | TKT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234304-A1 | N3-Pyridyl-Thiamine And Its Use In Cancer Treatments | AVEO PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | US | disclosed |
| US-20070292888-A1 | Methods for Measuring Enzyme Activities in Cells, Blood, Tumors and Tissues | GEN-PATH PHARMACEUTICALS, INC. (US) | 2007-12-20 | — | — | US | disclosed |
| WO-2005094803-A2 | N3-PYRIDYL-THIAMINE AND ITS USE IN CANCER TREATMENTS | AVEO PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | disclosed |
| WO-2005095636-A2 | METHODS FOR MEASURING ENZYME ACTIVITIES IN CELLS, BLOOD, TUMORS AND TISSUES | AVEO PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234304-A1 | N3-Pyridyl-Thiamine And Its Use In Cancer Treatments | SLC19A2, TYMS, NAMPT | TKT 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.