Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27716753 | 0.78 | HSD11B1 (0.45) | MEN1KMT2AALDH1A1GAAALOX15 | |
| Hydrochloric Acid SCHEMBL4878686 | 0.77 | HSD11B1 (0.44) | MEN1KMT2AALDH1A1GAAALOX15 | |
| SCHEMBL4881192 | 0.74 | P2RY12 (0.48) | ALDH1A1MAPTTSHRKDM4EP2RY12 | |
| SCHEMBL4100121 | 0.73 | P2RY12 (0.61) | P2RY12 | |
| SCHEMBL4881127 | 0.73 | P2RY12 (0.45) | MEN1KMT2AALDH1A1GAAP2RY12 | |
| SCHEMBL4876930 | 0.71 | P2RY12 (0.49) | ALDH1A1MAPTKDM4EP2RY12OPRK1 | |
| SCHEMBL3328558 | 0.70 | P2RY12 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL4881431 | 0.70 | L3MBTL1 (0.40) | MEN1KMT2AALDH1A1GAAALOX15 | |
| SCHEMBL3327054 | 0.68 | P2RY12 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL3221673 | 0.68 | P2RY12 (0.69) | KDM4EP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312208-A1 | Pyridine Analogues | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312208-A1 | Pyridine Analogues | P2RY12, P2RY11, P2RY1 | MEN1 1510/4885KMT2A 3584/4885ALDH1A1 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.