Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 5/20 | 0.33 |
| ▸ | CTSS | P25774 | 5/20 | 0.33 |
| ▸ | CTSB | P07858 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL27856444 | 0.85 | MAOB (0.37) | MAOBCTSLCTSSCTSBCTSK | |
| SCHEMBL80897 | 0.83 | TSHR (0.41) | ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL4881259 | 0.79 | MAOB (0.36) | MAOBCTSLCTSSCTSBCTSK | |
| SCHEMBL25408699 | 0.75 | — | — | |
| SCHEMBL4782196 | 0.74 | MAOB (0.43) | MAOBCTSLCTSSCTSBCTSK | |
| SCHEMBL4730931 | 0.74 | MAOB (0.43) | MAOBCTSLCTSSCTSBCTSK | |
| SCHEMBL887785 | 0.74 | TSHR (0.30) | TSHR | |
| SCHEMBL2252915 | 0.73 | TSHR (0.41) | ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL12380718 | 0.72 | FFAR1 (0.35) | CTSLCTSBCTSKALDH1A1LMNA | |
| SCHEMBL5831072 | 0.72 | CA1 (0.33) | ALDH1A1LMNATSHRKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261923-A1 | Alkene Mimics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261923-A1 | Alkene Mimics | PHOSPHO1, PARN, CHAMP1 | MAOB 4172/4885CTSL 664/4885CTSS 2059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.