SCHEMBL5831072

SCHEMBL5831072

CC(C)N(C(C)C)P(OCc1ccccc1)OCC(Cl)(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
TSHR P16473 2/20 0.32
MCL1 Q07820 1/20 0.32
KMT2A Q03164 1/20 0.32
IDO1 P14902 1/20 0.31
ALDH1A1 P00352 3/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
GLRA1 P23415 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80897 0.87 TSHR (0.41) CA1TSHRKMT2AIDO1ALDH1A1
SCHEMBL5831071 0.81 TSHR (0.32) TSHRKMT2AIDO1ALDH1A1LMNA
Acetonitrile SCHEMBL27856444 0.80 MAOB (0.37) TSHRKMT2AIDO1ALDH1A1
SCHEMBL12380718 0.77 FFAR1 (0.35) CA1TSHRKMT2AALDH1A1LMNA
SCHEMBL24027472 0.75 TSHR (0.36) CA1TSHRKMT2AIDO1ALDH1A1
SCHEMBL2261012 0.74 TSHR (0.39) CA1TSHRKMT2AIDO1ALDH1A1
SCHEMBL5970336 0.74 IDO1 (0.42) CA1KMT2AIDO1ALDH1A1HPGD
SCHEMBL2252915 0.74 TSHR (0.41) CA1TSHRKMT2AIDO1ALDH1A1
SCHEMBL2227585 0.73 TSHR (0.40) CA1TSHRKMT2AIDO1ALDH1A1
SCHEMBL4881254 0.72 MAOB (0.34) TSHRKMT2AALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037486-B1 Labelled phosphoinositides and analogues NUTRIMED BIOTECH (US) 2006-05-02 US disclosed
US-6376697-B1 Labelled phosphoinositides and analogues NUTRIMED BIOTECH 2002-04-23 US disclosed