Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methylpyrrolidone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.65 |
| ▸ | BRD2 | P25440 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpyrrolidone SCHEMBL7705049 | 0.92 | BRD4 (0.77) | BRD4BRD2LMNAALDH1A1KMT2A | |
| Methylpyrrolidone SCHEMBL10701586 | 0.90 | BRD4 (0.81) | BRD4BRD2LMNAALDH1A1KMT2A | |
| Methylpyrrolidone SCHEMBL4203176 | 0.89 | BRD4 (0.65) | BRD4BRD2LMNAALDH1A1KMT2A | |
| Methylpyrrolidone SCHEMBL28525083 | 0.88 | BRD4 (0.77) | BRD4BRD2LMNAALDH1A1KMT2A | |
| Methylpyrrolidone SCHEMBL28866005 | 0.88 | BRD4 (0.77) | BRD4BRD2LMNAALDH1A1KMT2A | |
| Methylpyrrolidone SCHEMBL1932845 | 0.87 | BRD4 (0.63) | BRD4BRD2LMNAALDH1A1KMT2A | |
| Methylpyrrolidone SCHEMBL1801243 | 0.84 | BRD4 (0.77) | BRD4BRD2LMNAALDH1A1KMT2A | |
| Methylpyrrolidone SCHEMBL27843521 | 0.84 | BRD4 (0.77) | BRD4BRD2LMNAALDH1A1KMT2A | |
| Methylpyrrolidone SCHEMBL28669219 | 0.83 | BRD4 (0.63) | BRD4BRD2LMNAALDH1A1KMT2A | |
| Methylpyrrolidone SCHEMBL28884394 | 0.82 | BRD4 (0.74) | BRD4BRD2LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014070270-A1 | ELECTROCHEMICAL ROUTE TO PREPARE HYDROCARBYL-FUNCTIONAL SILICON COMPOUNDS | DOW CORNING CORPORATION (US) | 2014-05-08 | — | — | WO | claimed |
| US-7459134-B2 | Method of decarbonating a combustion fume with extraction of the solvent contained in the purified fume | INSTITUT FRANCAIS DU PETROLE | 2008-12-02 | — | — | US | claimed |
| CN-112996835-B | Method for producing thermoplastic polyoxazolidone polymers | 科思创知识产权两合公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-113906072-A | Method for producing epoxy group-terminated polyoxazolidinones | 科思创知识产权两合公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-113166368-A | Process for producing thermoplastic polyoxazolidone polymers | 科思创知识产权两合公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112996835-A | Process for producing thermoplastic polyoxazolidone polymers | 科思创知识产权两合公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-110461504-A | Engagement metal thickener, conjugant and its manufacturing method and semiconductor device and its manufacturing method | HITACHI CHEMICAL CO LTD | 2019-11-15 | — | — | CN | disclosed |
| EP-3185346-B1 | ELECTRODE ASSEMBLY HAVING SPACE PART IN WHICH TAB-LEAD COUPLING PART OF ELECTRODE TABS AND ELECTRODE LEAD IS LOCATED | LG CHEMICAL LTD (KR) | 2018-09-19 | — | — | EP | disclosed |
| US-9444095-B1 | Method of making cathode active material, cathode and lithium secondary battery | INDUSTRY-ACADEMIA COOPERATION GROUP OF SEJONG UNIV (KR) | 2016-09-13 | — | — | US | disclosed |
| US-20160248079-A1 | METHOD OF MAKING CATHODE ACTIVE MATERIAL, CATHODE AND LITHIUM SECONDARY BATTERY | INDUSTRY-ACADEMIA COOP GROUP OF SEJONG UNIV (KR) | 2016-08-25 | — | — | US | disclosed |
| WO-2014070270-A1 | ELECTROCHEMICAL ROUTE TO PREPARE HYDROCARBYL-FUNCTIONAL SILICON COMPOUNDS | DOW CORNING CORPORATION (US) | 2014-05-08 | — | — | WO | disclosed |
| CN-101842079-A | Non-aqueous pharmaceutical compositions | ARCHIMEDES DEV LTD | 2010-09-22 | — | — | CN | disclosed |
| WO-2007074127-A1 | PROCESS TO MAKE A SULPHUR CONTAINING HYDROCARBON PRODUCT | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2007-07-05 | — | — | WO | disclosed |
| US-7132012-B2 | Phthalocyanine compound, ink, ink jet recording method and image forming method | FUJI PHOTO FILM CO., LTD. (JP) | 2006-11-07 | — | — | US | disclosed |
| US-20060017792-A1 | Phthalocyanine compound, ink, ink jet recording method and image forming method | FUJI PHOTO FILM CO., LTD. (JP) | 2006-01-26 | — | — | US | disclosed |
| US-20020061407-A1 | Abrasion resistant coating composition and coated articles | PPG INDUSTRIES OHIO, INC. | 2002-05-23 | — | — | US | disclosed |