SCHEMBL4881869

SCHEMBL4881869

O=C(CN1CCCNCC1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 6/20 0.49
CHRM1 P11229 6/20 0.49
CHRM3 P20309 4/20 0.49
CHRM4 P08173 3/20 0.49
CHRM5 P08912 3/20 0.49
CYP2D6 P10635 3/20 0.43
HTR1A P08908 2/20 0.43
OPRM1 P35372 2/20 0.43
KCNH2 Q12809 2/20 0.43
LMNA P02545 2/20 0.43
CXCR4 P61073 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ADRA2C P18825 1/20 0.42
CCR2 P41597 1/20 0.42
CXCL12 P48061 1/20 0.42
BLM P54132 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13592179 0.94 CHRM2 (0.54) CHRM2CHRM1CHRM3CHRM4CHRM5
SCHEMBL14003869 0.88 CHRM2 (0.46) CHRM2CHRM1CHRM3CHRM4CHRM5
SCHEMBL4882752 0.84 CHRM3 (0.43) CHRM2CHRM1CHRM3CHRM4CHRM5
SCHEMBL4887075 0.83 CHRM3 (0.53) CHRM2CHRM1CHRM3CHRM4CHRM5
SCHEMBL13592181 0.79 CHRM3 (0.53) CHRM2CHRM1CHRM3
Hydrochloric Acid SCHEMBL9192480 0.78 CHRM3 (0.52) CHRM2CHRM1CHRM3CHRM4CHRM5
SCHEMBL13592212 0.78 CHRM3 (0.55) CHRM2CHRM1CHRM3CHRM4CHRM5
SCHEMBL6765682 0.77 CHRM2 (0.74) CHRM2CHRM1CHRM3CHRM4CHRM5
SCHEMBL7646019 0.75 ALDH1A1 (0.60) CHRM3CYP2D6KCNH2LMNAKMT2A
SCHEMBL4887061 0.73 CHRM2 (0.48) CHRM2CHRM1CHRM3CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080280883-A1 Muscarinic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2008-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280883-A1 Muscarinic Receptor Antagonists CHRM3, CHRM5, CHRM2 CHRM2 3/4885CHRM1 5/4885CHRM3 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.