Benzene

Benzene

SCHEMBL4881895

c1ccc2cc3c(cc2c1)c1cc2ccccc2cc1c1cc2ccccc2cc31.c1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
HSD17B10 Q99714 5/20 0.53
HIF1A Q16665 1/20 0.53
CYP1B1 Q16678 1/20 0.53
CYP2A6 P11509 6/20 0.50
ALOX12 P18054 1/20 0.50
NQO1 P15559 1/20 0.50
TDP1 Q9NUW8 2/20 0.47
TSHR P16473 1/20 0.47
NQO2 P16083 1/20 0.45
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
CYP1A2 P05177 3/20 0.43
CYP3A4 P08684 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
HPGD P15428 3/20 0.42
KDM4E B2RXH2 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL190942 0.96 ALDH1A1 (0.56) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
SCHEMBL29423353 0.96 ALDH1A1 (0.56) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
SCHEMBL28463321 0.96 ALDH1A1 (0.56) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
Anthracene SCHEMBL28787108 0.92 ALDH1A1 (0.53) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
Benzo[B]Triphenylene SCHEMBL29374595 0.89 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
Benzo[B]Triphenylene SCHEMBL29628013 0.89 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
SCHEMBL4855544 0.89 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
Benzo[B]Triphenylene SCHEMBL71635 0.89 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
Benzo[B]Triphenylene SCHEMBL17537048 0.86 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
SCHEMBL415471 0.86 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed