Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A3 | O75751 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 3/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.52 |
| ▸ | MTOR | P42345 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metiprenaline SCHEMBL3217916 | 0.87 | SLC22A3 (1.00) | SLC22A3TSHRCYP3A4NFKB1BLM | |
| Metiprenaline SCHEMBL2109418 | 0.87 | SLC22A3 (1.00) | SLC22A3TSHRCYP3A4NFKB1BLM | |
| Metiprenaline SCHEMBL3226665 | 0.87 | SLC22A3 (1.00) | SLC22A3TSHRCYP3A4NFKB1BLM | |
| Metiprenaline SCHEMBL3220256 | 0.86 | SLC22A3 (0.97) | SLC22A3TSHRCYP3A4NFKB1BLM | |
| Metiprenaline SCHEMBL3207430 | 0.86 | SLC22A3 (0.97) | SLC22A3TSHRCYP3A4NFKB1BLM | |
| SCHEMBL4627060 | 0.86 | SLC22A3 (0.58) | SLC22A3TSHRCYP3A4NFKB1BLM | |
| Metiprenaline SCHEMBL5319662 | 0.84 | SLC22A3 (0.94) | SLC22A3TSHRCYP3A4NFKB1BLM | |
| SCHEMBL4626897 | 0.84 | MAPT (0.73) | SLC22A3TSHRCYP3A4NFKB1BLM | |
| SCHEMBL31364250 | 0.82 | TSHR (1.00) | SLC22A3TSHRCYP3A4NFKB1BLM | |
| SCHEMBL31254086 | 0.82 | TSHR (1.00) | SLC22A3TSHRCYP3A4NFKB1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | claimed |
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | HRH3, OPRL1, HRH2 | SLC22A3 777/4885TSHR 974/4885CYP3A4 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.