Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.73 |
| ▸ | TSHR | P16473 | 5/20 | 0.73 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.73 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.73 |
| ▸ | MTOR | P42345 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.73 |
| ▸ | DRD2 | P14416 | 2/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4387242 | 0.86 | MAPT (0.74) | MAPTADRB2TDP1KDM4EHSD17B10 | |
| SCHEMBL4627996 | 0.85 | ADRB2 (0.54) | MAPTADRB2TDP1KDM4EHSD17B10 | |
| Levisoprenaline SCHEMBL29620666 | 0.85 | MAPT (1.00) | MAPTADRB2TDP1KDM4EHSD17B10 | |
| Isoproterenol SCHEMBL29519146 | 0.85 | MAPT (1.00) | MAPTADRB2TDP1KDM4EHSD17B10 | |
| Isoproterenol SCHEMBL29386243 | 0.85 | MAPT (1.00) | MAPTADRB2TDP1KDM4EHSD17B10 | |
| Isoproterenol SCHEMBL3253794 | 0.85 | MAPT (1.00) | MAPTADRB2TDP1KDM4EHSD17B10 | |
| Isoproterenol SCHEMBL4166 | 0.85 | MAPT (1.00) | MAPTADRB2TDP1KDM4EHSD17B10 | |
| Isoproterenol SCHEMBL4165 | 0.85 | MAPT (1.00) | MAPTADRB2TDP1KDM4EHSD17B10 | |
| Levisoprenaline SCHEMBL250806 | 0.85 | MAPT (1.00) | MAPTADRB2TDP1KDM4EHSD17B10 | |
| SCHEMBL4882170 | 0.84 | SLC22A3 (0.77) | MAPTADRB2TDP1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | disclosed |
| EP-1896393-A1 | THE TREATMENT OF INFLAMMATORY DISORDERS AND PAIN | Sosei R&D Ltd. (GB) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007003896-A1 | THE TREATMENT OF INFLAMMATORY DISORDERS AND PAIN | SOSEI R & D LTD. (GB) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | HRH3, OPRL1, HRH2 | MAPT 4250/4885ADRB2 131/4885TDP1 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.