Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3340590 | 0.78 | MAPT (0.46) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL4801854 | 0.74 | FLT3 (0.35) | HPGDALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL4882593 | 0.67 | ADORA1 (0.44) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL7863728 | 0.65 | ALDH1A1 (0.60) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL11829820 | 0.64 | ALDH1A1 (0.58) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL4799024 | 0.64 | KMT2A (0.53) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL4960018 | 0.64 | — | — | |
| SCHEMBL31151793 | 0.62 | HPGD (0.65) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL8573730 | 0.62 | HPGD (0.65) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL1822990 | 0.61 | NPC1 (0.47) | HPGDKMT2AMEN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052804-A1 | THIAZOLHYDRAZIDES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-08 | — | — | WO | disclosed |