Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 9/20 | 0.75 |
| ▸ | CDK2 | P24941 | 9/20 | 0.75 |
| ▸ | GAA | P10253 | 7/20 | 0.75 |
| ▸ | MAPT | P10636 | 7/20 | 0.75 |
| ▸ | MEN1 | O00255 | 7/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.75 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.75 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.75 |
| ▸ | CDK9 | P50750 | 5/20 | 0.75 |
| ▸ | GFER | P55789 | 4/20 | 0.75 |
| ▸ | CDK4 | P11802 | 4/20 | 0.75 |
| ▸ | CCND1 | P24385 | 4/20 | 0.75 |
| ▸ | CDK7 | P50613 | 3/20 | 0.75 |
| ▸ | CCNH | P51946 | 3/20 | 0.75 |
| ▸ | RAB9A | P51151 | 3/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.75 |
| ▸ | CDK1 | P06493 | 2/20 | 0.75 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.75 |
| ▸ | NPC1 | O15118 | 2/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882884 | 1.00 | CCNE1 (0.75) | CCNE1CDK2GAAMAPTMEN1 | |
| SCHEMBL3310182 | 0.86 | CCNE1 (1.00) | CCNE1CDK2GAAMAPTMEN1 | |
| SCHEMBL3836615 | 0.86 | MAPT (1.00) | CCNE1CDK2GAAMAPTMEN1 | |
| SCHEMBL12589685 | 0.86 | CCNE1 (1.00) | CCNE1CDK2GAAMAPTMEN1 | |
| SCHEMBL3839801 | 0.86 | GAA (1.00) | CCNE1CDK2GAAMAPTMEN1 | |
| SCHEMBL3837703 | 0.86 | MAPT (0.71) | CCNE1CDK2GAAMAPTMEN1 | |
| SCHEMBL3837559 | 0.85 | CCNE1 (1.00) | CCNE1CDK2GAAMAPTMEN1 | |
| SCHEMBL3837556 | 0.85 | CCNE1 (1.00) | CCNE1CDK2GAAMAPTMEN1 | |
| SCHEMBL4890889 | 0.84 | CCNE1 (0.69) | CCNE1CDK2GAAMAPTMEN1 | |
| SCHEMBL4893821 | 0.84 | CCNE1 (0.69) | CCNE1CDK2GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357673-B2 | 4-arylazo-3,5-diamino-pyrazole compounds and use thereof | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2013-01-22 | — | — | US | disclosed |
| US-20080312238-A1 | 4-Arylazo-3,5-Diamino-Pyrazole Compounds and Use Thereof | INSTITUTE OF EXPERIMENTAL BONTANY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC, V.V.I. (CZ) | 2008-12-18 | — | — | US | disclosed |
| EP-1786779-A1 | 4-ARYLAZO-3,5-DIAMINO-PYRAZOLE COMPOUNDS AND USE THEREOF | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006024858-A1 | 4-ARYLAZO-3,5-DIAMINO-PYRAZOLE COMPOUNDS AND USE THEREOF | INSTITUTE OF EXPERIMENTAL BOTANY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312238-A1 | 4-Arylazo-3,5-Diamino-Pyrazole Compounds and Use Thereof | CDK9, CDK3, CDK19 | CCNE1 93/4885CDK2 13/4885GAA 1275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.