SCHEMBL4883020

SCHEMBL4883020

OC(CNC1CCN(Cc2ccccc2)C1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BCHE P06276 14/20 0.59
BACE1 P56817 14/20 0.59
ACHE P22303 13/20 0.59
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
MITF O75030 1/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
DRD2 P14416 1/20 0.47
DRD4 P21917 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21989908 0.81 BACE1 (0.66) BCHEBACE1ACHE
SCHEMBL22031918 0.81 BACE1 (0.66) BCHEBACE1ACHE
SCHEMBL4882920 0.81 FUCA1 (0.41)
SCHEMBL4882994 0.77 BACE1 (0.60) BCHEBACE1ACHE
SCHEMBL4131291 0.75 ACHE (1.00) BCHEBACE1ACHEMEN1KMT2A
SCHEMBL5692288 0.75 ACHE (1.00) BCHEBACE1ACHEMEN1KMT2A
SCHEMBL7504191 0.74 BCHE (0.75) BCHEBACE1ACHE
SCHEMBL1908453 0.74 BCHE (0.75) BCHEBACE1ACHE
Hydrochloric Acid SCHEMBL9639310 0.74 ACHE (0.97) BCHEBACE1ACHEMEN1KMT2A
SCHEMBL1781710 0.74 BCHE (0.75) BCHEBACE1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080280883-A1 Muscarinic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2008-11-13 US claimed
EP-1794161-A2 MUSCARINIC RECEPTOR ANTAGONISTS Ranbaxy Laboratories Limited (IN) 2007-06-13 EP claimed
WO-2006032994-A2 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2006-03-30 WO claimed
US-20080280883-A1 Muscarinic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2008-11-13 US disclosed
EP-1794161-A2 MUSCARINIC RECEPTOR ANTAGONISTS Ranbaxy Laboratories Limited (IN) 2007-06-13 EP disclosed
WO-2006032994-A2 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2006-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280883-A1 Muscarinic Receptor Antagonists CHRM3, CHRM5, CHRM2 BCHE 256/4885BACE1 3482/4885ACHE 92/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.