Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 19/20 | 1.00 |
| ▸ | BACE1 | P56817 | 19/20 | 1.00 |
| ▸ | BCHE | P06276 | 18/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692288 | 1.00 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9639310 | 0.98 | ACHE (0.97) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL22426273 | 0.92 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL22426276 | 0.92 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL28496734 | 0.91 | BCHE (0.83) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL28511753 | 0.91 | BCHE (0.83) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL14367985 | 0.90 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL4982345 | 0.86 | ACHE (0.75) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL4635732 | 0.86 | ACHE (0.75) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL1908453 | 0.86 | BCHE (0.75) | ACHEBACE1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124636-A1 | CHEMICAL COMPOUNDS | PFIZER INC. | 2009-05-14 | — | — | US | disclosed |
| US-20090124636-A1 | CHEMICAL COMPOUNDS | PFIZER INC. | 2009-05-14 | — | — | US | disclosed |
| US-20090124636-A1 | CHEMICAL COMPOUNDS | PFIZER INC. | 2009-05-14 | — | — | US | disclosed |
| WO-2007116313-A2 | PYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE CCR5 RECEPTORS | PFIZER LIMITED (GB) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124636-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CX3CR1 | ACHE 1798/4885BACE1 3307/4885BCHE 4387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.