Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884377 | 0.88 | CHRM2 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2CHRM2 | |
| SCHEMBL4884344 | 0.85 | CHRM2 (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2CHRM2 | |
| SCHEMBL4879639 | 0.82 | CHRM2 (0.67) | ALDH1A1NPC1RAB9ASMN1; SMN2CHRM2 | |
| SCHEMBL574530 | 0.82 | CHRM2 (0.67) | ALDH1A1NPC1RAB9ASMN1; SMN2CHRM2 | |
| SCHEMBL4883077 | 0.82 | CHRM2 (0.41) | ALDH1A1NPC1CHRM2CHRM1CHRM5 | |
| Hydrochloric Acid SCHEMBL4771342 | 0.81 | CHRM2 (0.66) | ALDH1A1NPC1RAB9ASMN1; SMN2CHRM2 | |
| SCHEMBL4662576 | 0.81 | CHRM2 (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2CHRM2 | |
| SCHEMBL4874634 | 0.81 | CHRM2 (0.41) | ALDH1A1NPC1CHRM2CHRM1CHRM5 | |
| Iodide SCHEMBL4661193 | 0.80 | CHRM2 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2CHRM2 | |
| SCHEMBL4875764 | 0.80 | CHRM2 (0.38) | ALDH1A1CHRM2CHRM1CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838659-B1 | PROCESS FOR PREPARATION OF N,N-DIISOPROPYL-3-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPYLAMINE | LEK PHARMACEUTICALS (SI) | 2015-07-15 | — | — | EP | disclosed |
| US-20080045602-A1 | Process for Preparation of 3-(2-Hydroxy-5Methylphenyl)-N, N-Disopropyl-3-Phenylpropylamine | LEK PHARMACEUTICALS, D.D. (SI) | 2008-02-21 | — | — | US | disclosed |
| EP-1838659-A1 | PROCESS FOR PREPARATION OF 3-(2-HYDROXY-5-METHYLPHENYL)-N,N-DIISOPROPYL-3PHENYLPROPYLAMINE | LEK Pharmaceuticals D.D. (SI) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006066931-A1 | PROCESS FOR PREPARATION OF 3-(2-HYDROXY-5-METHYLPHENYL)-N,N-DIISOPROPYL-3PHENYLPROPYLAMINE | LEK PHARMACEUTICALS D.D. (SI) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045602-A1 | Process for Preparation of 3-(2-Hydroxy-5Methylphenyl)-N, N-Disopropyl-3-Phenylpropylamine | SLC6A3, PNMT, PIR | ALDH1A1 1210/4885NPC1 1286/4885RAB9A 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.