Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978702 | 0.88 | DDB1 (0.41) | DDB1CRBNPTPN11KDM4EALDH1A1 | |
| SCHEMBL5442448 | 0.87 | DDB1 (0.42) | DDB1CRBNPTPN11KDM4EALDH1A1 | |
| SCHEMBL4183925 | 0.85 | DDB1 (0.37) | DDB1CRBNPTPN11KDM4EALDH1A1 | |
| SCHEMBL4183629 | 0.85 | DDB1 (0.38) | DDB1CRBNPTPN11KDM4EALDH1A1 | |
| SCHEMBL4174568 | 0.83 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10STAT3 | |
| SCHEMBL4186478 | 0.82 | DDB1 (0.39) | DDB1CRBNPTPN11KDM4EALDH1A1 | |
| SCHEMBL4180098 | 0.81 | DDB1 (0.37) | DDB1CRBNPTPN11KDM4EALDH1A1 | |
| SCHEMBL4139977 | 0.78 | DDB1 (0.36) | DDB1CRBNKDM4EALDH1A1HPGD | |
| SCHEMBL4186260 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10STAT3 | |
| SCHEMBL3974096 | 0.74 | LMNA (0.56) | DDB1CRBNPTPN11KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096829-A1 | Macrolone Compounds | GLAXO GROUP LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096829-A1 | Macrolone Compounds | MRPL21, MRPS18A, MRPL19 | DDB1 3374/4885CRBN 4542/4885PTPN11 3333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.