Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5442448 | 0.90 | DDB1 (0.42) | DDB1CRBNSTAT3ADRB2ALDH1A1 | |
| SCHEMBL3978702 | 0.85 | DDB1 (0.41) | DDB1CRBNSTAT3ALDH1A1KDM4E | |
| SCHEMBL4136760 | 0.83 | DDB1 (0.38) | DDB1CRBNADRB2BCHECNR2 | |
| SCHEMBL3815499 | 0.79 | LMNA (0.50) | DDB1CRBNALDH1A1KDM4EHPGD | |
| SCHEMBL4129107 | 0.79 | KDM4E (0.49) | DDB1CRBNALDH1A1KDM4EHPGD | |
| SCHEMBL4129106 | 0.79 | KDM4E (0.49) | DDB1CRBNALDH1A1KDM4EHPGD | |
| SCHEMBL4883376 | 0.78 | DDB1 (0.37) | DDB1CRBNSTAT3ADRB2ALDH1A1 | |
| SCHEMBL3291116 | 0.78 | LMNA (0.37) | DDB1CRBNBCHECNR2ALDH1A1 | |
| SCHEMBL3981476 | 0.76 | MTNR1A (0.42) | ADRB2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4180098 | 0.75 | DDB1 (0.37) | DDB1CRBNSTAT3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111760-A1 | MACROLONE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111760-A1 | MACROLONE COMPOUNDS | CYP51A1, MRPL21, MYD88 | DDB1 3765/4885CRBN 3533/4885STAT3 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.