Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 8/20 | 0.56 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888740 | 1.00 | DGAT1 (0.56) | DGAT1SOAT1DGAT2 | |
| SCHEMBL4883330 | 0.89 | DGAT1 (0.70) | DGAT1SOAT1DGAT2 | |
| SCHEMBL4883344 | 0.89 | DGAT1 (0.70) | DGAT1SOAT1DGAT2 | |
| SCHEMBL5306102 | 0.89 | DGAT1 (0.52) | DGAT1SOAT1DGAT2 | |
| SCHEMBL5307953 | 0.86 | DGAT1 (0.51) | DGAT1SOAT1DGAT2 | |
| SCHEMBL4808228 | 0.84 | DGAT1 (0.51) | DGAT1SOAT1DGAT2 | |
| SCHEMBL4808208 | 0.84 | DGAT1 (0.51) | DGAT1SOAT1DGAT2 | |
| SCHEMBL3546823 | 0.83 | DGAT1 (0.80) | DGAT1SOAT1DGAT2 | |
| SCHEMBL3546828 | 0.83 | DGAT1 (0.80) | DGAT1SOAT1DGAT2 | |
| SCHEMBL4815841 | 0.82 | DGAT1 (0.54) | DGAT1SOAT1DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129319-A1 | SALTS OF OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | disclosed |