SCHEMBL4885281

SCHEMBL4885281

O=C(O)Cc1cccc(NCn2ccc(=O)[nH]c2=O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA9 Q16790 1/20 0.44
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
ALDH1A1 P00352 2/20 0.41
SELP P16109 2/20 0.41
SELE P16581 2/20 0.41
HPSE Q9Y251 1/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
DUT P33316 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5523734 0.70 SELP (0.50) SELPSELEHPSENR1H4SELL
SCHEMBL7339625 0.70 FFAR1 (0.62)
SCHEMBL13539348 0.68 P2RY2 (0.52) ALDH1A1KDM4EMEN1KMT2AATM
SCHEMBL2899640 0.67 ALDH1A1 (0.59) CA1CA2CA4CA9ALDH1A1
SCHEMBL13370136 0.67 SELP (0.56) SELPSELEHPSEKDM4ELMNA
SCHEMBL8208474 0.67 MAPT (0.58)
SCHEMBL11073287 0.66 HPSE (0.52) SELPSELEHPSEKDM4ENR1H4
SCHEMBL2468368 0.66 AKR1B1 (0.57) ALDH1A1SELPSELEHPSEMEN1
SCHEMBL3104224 0.66 NR1H4 (0.56) SELPSELEHPSEMEN1KMT2A
SCHEMBL3273166 0.66 SELP (0.55) SELPSELEHPSEKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7319141-B2 Stem cell growth factor-like polypeptides KIRIN BEER KABUSHIKI KAISHA (JP) 2008-01-15 US disclosed
US-20050059073-A1 Method and materials relating to novel stem cell growth factor-like polypeptides and polynucleotides KYOWA HAKKO KIRIN CO., LTD. (JP) 2005-03-17 US disclosed
US-20020055147-A1 Human chemokine beta-13 NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2002-05-09 US disclosed