SCHEMBL2899640

SCHEMBL2899640

O=C(O)Cn1ccc(=O)[nH]c1=O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.59
LMNA P02545 1/20 0.59
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
ATM Q13315 1/20 0.51
CA1 P00915 5/20 0.50
CA2 P00918 5/20 0.50
CA4 P22748 5/20 0.50
CA9 Q16790 5/20 0.50
L3MBTL1 Q9Y468 1/20 0.48
PKM P14618 1/20 0.47
DUT P33316 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28803795 0.93 ALDH1A1 (0.54) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL28803862 0.92 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL29167329 0.90 ALDH1A1 (0.51) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL11983580 0.83 ALDH1A1 (0.58) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL11710759 0.83 ALDH1A1 (0.58) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL11710750 0.83 ALDH1A1 (0.58) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL1673256 0.81 KMT2A (0.42) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL8135756 0.81 DUT (0.58) ALDH1A1LMNAL3MBTL1DUT
SCHEMBL667245 0.80 ALDH1A1 (0.59) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL27703786 0.80 ALDH1A1 (0.55) ALDH1A1LMNAKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114702514-B Copper tetrafluoroborate complex of 2,2' -bipyridine and uracil-1-yl acetate, and preparation method and application thereof 温州大学新材料与产业技术研究院 2024-01-02 CN claimed
CN-114702514-A 2,2' -bipyridine and uracil-1-base acetic acid copper tetrafluoroborate complex and preparation method and application thereof 温州大学新材料与产业技术研究院 2022-07-05 CN claimed
US-20190262794-A1 SUBSTRATES, SYSTEMS, AND METHODS FOR NUCLEIC ACID ARRAY SYNTHESIS VIBRANT HOLDINGS, LLC 2019-08-29 US claimed
EP-3402897-A1 SUBSTRATES, SYSTEMS, AND METHODS FOR NUCLEIC ACID ARRAY SYNTHESIS Vibrant Holdings, LLC (US) 2018-11-21 EP claimed
WO-2017117292-A1 SUBSTRATES, SYSTEMS, AND METHODS FOR NUCLEIC ACID ARRAY SYNTHESIS VIBRANT HOLDINGS, LLC (US) 2017-07-06 WO claimed
EP-0792283-A1 SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH CHIRON CORPORATION (US) 1997-09-03 EP claimed
WO-1996015143-A1 SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH CHIRON CORPORATION (US) 1996-05-23 WO claimed
US-20260072035-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS UNIV NORTHEASTERN (US) 2026-03-12 US disclosed
EP-4620948-A1 LIPID COMPOUND AND COMPOSITION FOR DELIVERY OF ACTIVE SUBSTANCE Korea Research Institute of Bioscience and Biotechnology (KR) 2025-09-24 EP disclosed
US-20250236612-A1 RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS, INC. 2025-07-24 US disclosed
WO-2025092267-A1 NUCLEOSIDE AND NUCLEOTIDE ANALOG, DOUBLE-STRANDED OLIGONUCLEOTIDE AND CONJUGATE CONTAINING NUCLEOTIDE ANALOG, AND USE THEREOF 北京炫景瑞医药科技有限公司 2025-05-08 WO disclosed
EP-4511513-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS Northeastern University (US) 2025-02-26 EP disclosed
US-12180193-B2 Accelerating fibrosarcoma protein degrading compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2024-12-31 US disclosed
WO-1995019779-A1 DELTEX PROTEINS, NUCLEIC ACIDS, AND ANTIBODIES, AND RELATED METHODS AND COMPOSITIONS YALE UNIVERSITY (US) 1995-07-27 WO disclosed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US disclosed
EP-0504279-A4 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES 1993-02-17 EP disclosed
EP-0504279-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES. CHEMGEN CORP (US) 1992-09-23 EP disclosed
WO-1991009130-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES CHEMGEN CORPORATION (US) 1991-06-27 WO disclosed
US-4008221-A BACTERICIDE, ANTIBIOTIC RICHARDSON-MERRELL INC. (US) 1977-02-15 US disclosed
US-3956288-A 7-[(2,4-Dioxo-1-pyrimidinyl)acylamino]cephalosporin derivatives RICHARDSON-MERRELL INC. (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12180193-B2 Accelerating fibrosarcoma protein degrading compounds and associated methods of use CRBN, RBX1, ARAF ALDH1A1 2803/4885LMNA 2304/4885KDM4E 2141/4885
US-20250236612-A1 RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE CRBN, RBX1, ARAF ALDH1A1 2856/4885LMNA 2101/4885KDM4E 2141/4885
US-20260072035-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS DNMT3A, APEX1, CHAMP1 ALDH1A1 941/4885LMNA 664/4885KDM4E 1562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.