SCHEMBL4885515

SCHEMBL4885515

Cc1c(C(=O)O)nn(-c2ccc(Cl)c(Cl)c2)c1-c1ccc(Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RPA1 P27694 2/20 0.57
CNR1 P21554 7/20 0.53
CNR2 P34972 9/20 0.52
PTGS2 P35354 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277784 0.90 CNR1 (0.62) RPA1CNR1CNR2PTGS2
Hydrochloric Acid SCHEMBL278149 0.88 CNR1 (0.61) RPA1CNR1CNR2PTGS2
SCHEMBL4872470 0.85 GABRA2 (0.59) CNR1CNR2
SCHEMBL29838955 0.84 CYP1A2 (0.57) CNR1CNR2PTGS2
SCHEMBL16197705 0.84 CNR1 (0.57) CNR1CNR2PTGS2
SCHEMBL924033 0.81 CNR2 (0.76) CNR1CNR2
SCHEMBL30571219 0.81 CNR2 (0.76) CNR1CNR2
SCHEMBL277080 0.81 CNR1 (0.54) RPA1CNR1CNR2PTGS2
Hydrochloric Acid SCHEMBL3002214 0.80 CNR2 (0.74) CNR1CNR2
SCHEMBL6341478 0.80 PTGS2 (0.79) CNR1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008062480-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF RIMONABANT IND-SWIFT LABORATORIES LIMITED (IN) 2008-05-29 WO claimed