SCHEMBL4885689

SCHEMBL4885689

CCCCc1cc(C(=O)O)cc(C(=O)OCc2ccccc2)c1C(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.54
ALDH1A1 P00352 5/20 0.54
L3MBTL1 Q9Y468 5/20 0.54
TSHR P16473 4/20 0.54
CYP3A4 P08684 2/20 0.54
MAPK1 P28482 2/20 0.54
KMT2A Q03164 4/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
LMNA P02545 1/20 0.42
RAB9A P51151 4/20 0.41
NPC1 O15118 1/20 0.41
MEN1 O00255 1/20 0.41
HPGD P15428 2/20 0.40
MAPT P10636 1/20 0.40
GAA P10253 1/20 0.40
PTGER1 P34995 1/20 0.39
PTGER4 P35408 1/20 0.39
PTGER3 P43115 1/20 0.39
PTGER2 P43116 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3203136 0.83 TSHR (0.63) TDP1ALDH1A1L3MBTL1TSHRCYP3A4
SCHEMBL7736627 0.82 ALDH1A1 (0.53) TDP1ALDH1A1L3MBTL1TSHRCYP3A4
SCHEMBL27788499 0.81 TDP1 (0.58) TDP1ALDH1A1L3MBTL1TSHRCYP3A4
SCHEMBL4894208 0.81 TSHR (0.54) TDP1ALDH1A1L3MBTL1TSHRCYP3A4
SCHEMBL1232508 0.79 ALDH1A1 (0.69) TDP1ALDH1A1L3MBTL1TSHRCYP3A4
SCHEMBL317668 0.79 TSHR (0.50) ALDH1A1TSHRCYP3A4MAPK1LMNA
SCHEMBL316164 0.79 TSHR (0.50) ALDH1A1TSHRCYP3A4MAPK1LMNA
SCHEMBL3851805 0.79 TSHR (0.50) ALDH1A1TSHRCYP3A4MAPK1LMNA
SCHEMBL17817820 0.79 TSHR (0.50) ALDH1A1TSHRCYP3A4MAPK1LMNA
SCHEMBL3203139 0.79 TDP1 (0.61) TDP1ALDH1A1L3MBTL1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080306190-A1 Composition of matter based on alkyl benzyl esters LANXESS DEUTSCHLAND GMBH (DE) 2008-12-11 US claimed
US-20080004387-A1 Alkyl benzyl esters of polycarboxylic acids LANXESS DEUTSCHLAND GMBH (DE) 2008-01-03 US claimed
US-20080004387-A1 Alkyl benzyl esters of polycarboxylic acids LANXESS DEUTSCHLAND GMBH (DE) 2008-01-03 US disclosed