Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3203139 | 0.83 | TDP1 (0.61) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL4885689 | 0.82 | TDP1 (0.54) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL7733831 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL7734770 | 0.81 | PTPN1 (0.46) | HSD17B10SLC6A3MAPTPTGESTOP2A | |
| SCHEMBL23812449 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL1164650 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL3818532 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL4885723 | 0.79 | TSHR (0.55) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL1232508 | 0.79 | ALDH1A1 (0.69) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL7723904 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399318-B1 | ANTIGEN WHICH IS CONJUGATE OF CARRIER PROTEIN AND PHTHALIC ACID ESTER OF DEFINED STRUCTURE; FOR DETECTION AND MEASUREMENT OF PLASTICIZERS IN ENVIRONMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |