Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5106897 | 1.00 | EPHX2 (0.55) | EPHX2LMNAGAATRPV1HDAC3 | |
| SCHEMBL24575927 | 0.86 | EPHX2 (0.64) | EPHX2LMNAGAATRPV1HDAC3 | |
| SCHEMBL10797865 | 0.84 | EPHX2 (0.57) | EPHX2LMNAGAATRPV1SSTR4 | |
| SCHEMBL9560347 | 0.84 | EPHX2 (0.57) | EPHX2LMNAGAATRPV1SSTR4 | |
| SCHEMBL14025088 | 0.82 | EPHX2 (0.60) | EPHX2LMNAGAATRPV1HDAC3 | |
| SCHEMBL16477697 | 0.81 | EPHX2 (0.56) | EPHX2LMNAGAATRPV1HDAC3 | |
| SCHEMBL16480210 | 0.79 | EPHX2 (0.60) | EPHX2LMNAGAATRPV1HDAC3 | |
| SCHEMBL14004671 | 0.79 | EPHX2 (0.60) | EPHX2LMNAGAATRPV1HDAC3 | |
| SCHEMBL7263715 | 0.78 | LMNA (0.61) | EPHX2LMNAGAASSTR4METAP2 | |
| SCHEMBL8518963 | 0.78 | LMNA (0.61) | EPHX2LMNAGAASSTR4METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3086844-A | — | — | None | — | — | JP | disclosed |
| US-20080103207-A1 | TOPICAL CERAMIDE COMPOSITIONS AND METHODS OF USE | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2008-05-01 | — | — | US | disclosed |
| JP-H0386844-A | OPTICAL RESOLUTION OF ALLETHRIN OPTICAL ISOMER MIXTURE | JIYUUKA BUNSEKI CENTER:KK | 1991-04-11 | — | — | JP | disclosed |