SCHEMBL9560347

SCHEMBL9560347

CC(C)[C@H](NC(=O)N[C@@H](C)c1cccc2ccccc12)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.57
LMNA P02545 1/20 0.52
GAA P10253 1/20 0.52
TRPV1 Q8NER1 2/20 0.50
SSTR4 P31391 1/20 0.50
METAP2 P50579 1/20 0.48
METAP1 P53582 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
OPRM1 P35372 1/20 0.47
OPRD1 P41143 1/20 0.47
OPRK1 P41145 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10797865 1.00 EPHX2 (0.57) EPHX2LMNAGAATRPV1SSTR4
SCHEMBL24575927 0.88 EPHX2 (0.64) EPHX2LMNAGAATRPV1SSTR4
SCHEMBL14025088 0.84 EPHX2 (0.60) EPHX2LMNAGAATRPV1SSTR4
SCHEMBL4885710 0.84 EPHX2 (0.55) EPHX2LMNAGAATRPV1SSTR4
SCHEMBL5106897 0.84 EPHX2 (0.55) EPHX2LMNAGAATRPV1SSTR4
SCHEMBL14004671 0.81 EPHX2 (0.60) EPHX2LMNAGAATRPV1SSTR4
SCHEMBL16480210 0.81 EPHX2 (0.60) EPHX2LMNAGAATRPV1SSTR4
SCHEMBL8518963 0.81 LMNA (0.61) EPHX2LMNAGAASSTR4METAP2
SCHEMBL7263715 0.81 LMNA (0.61) EPHX2LMNAGAASSTR4METAP2
SCHEMBL2934798 0.81 LMNA (0.61) EPHX2LMNAGAASSTR4METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0299793-B1 PACKING MATERIALS FOR ANALYSING ENANTIOMER MIXTURES BY LIQUID CHROMATOGRAPHY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-31 EP disclosed
US-4963254-A INORGANIC CARRIER HAVING GRAFTED AN ORGANOSILANE AND A CARBON REPRESENTING ASYMMETRIC; ANALYSIS FOR ENANTIOMORPHS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-16 US disclosed
EP-0299793-A2 Packing materials for analysing enantiomer mixtures by liquid chromatography SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-01-18 EP disclosed
EP-0105745-B1 PACKING MATERIALS FOR CHROMATOGRAPHIC USE AND THEIR EMPLOYMENT IN ANALYSING ENANTIOMERIC MIXTURES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-12-16 EP disclosed
US-4512898-A ORGANOSILANE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-04-23 US disclosed
EP-0105745-A2 Packing materials for chromatographic use and their employment in analysing enantiomeric mixtures SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-04-18 EP disclosed