Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885726 | 0.86 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1ROCK1GAA | |
| SCHEMBL3569040 | 0.75 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1LMNAROCK1 | |
| SCHEMBL3554974 | 0.73 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL28949886 | 0.72 | ALDH1A1 (0.54) | CYP3A4KMT2AALDH1A1LMNAGAA | |
| SCHEMBL13316448 | 0.71 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL4897484 | 0.71 | ABL1 (0.52) | ALDH1A1GAAMAPT | |
| SCHEMBL3564749 | 0.70 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL2572266 | 0.70 | ABL1 (0.55) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL4737145 | 0.70 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL24885815 | 0.69 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTNFKBIARELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146570-A1 | Chemical Compounds | ASTRAZENECA AB (SE) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146570-A1 | Chemical Compounds | BRAF, RAF1, NRAS | CYP3A4 2085/4885MEN1 168/4885CYP1A2 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.