Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 14/20 | 0.64 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.51 |
| ▸ | KYAT3 | Q6YP21 | 2/20 | 0.51 |
| ▸ | GOT1 | P17174 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22631177 | 0.79 | AADAT (0.58) | AADATKYAT1KYAT3GOT1KDM4E | |
| SCHEMBL3779303 | 0.78 | AADAT (1.00) | AADATKYAT1KYAT3GOT1KDM4E | |
| SCHEMBL16612984 | 0.78 | AADAT (1.00) | AADATKYAT1KYAT3GOT1KDM4E | |
| SCHEMBL3786010 | 0.78 | AADAT (1.00) | AADATKYAT1KYAT3GOT1KDM4E | |
| SCHEMBL5668062 | 0.78 | AADAT (0.43) | AADATKYAT1KYAT3GOT1KDM4E | |
| Hydrochloric Acid SCHEMBL16612967 | 0.77 | AADAT (0.97) | AADATKYAT1KYAT3GOT1KDM4E | |
| Hydrochloric Acid SCHEMBL16612968 | 0.77 | AADAT (0.97) | AADATKYAT1KYAT3GOT1KDM4E | |
| Hydrochloric Acid SCHEMBL16612966 | 0.77 | AADAT (0.97) | AADATKYAT1KYAT3GOT1KDM4E | |
| SCHEMBL5321137 | 0.76 | AADAT (0.46) | AADATKDM4EALDH1A1GAA | |
| SCHEMBL31381632 | 0.76 | AADAT (0.64) | AADATKYAT1KYAT3GOT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850287-B2 | Means and methods for breaking noncovalent binding interactions between molecules | HET NEDERLANDS KANKER INSTITUUT (NL) | 2017-12-26 | — | — | US | disclosed |
| US-20170145060-A9 | MEANS AND METHODS FOR BREAKING NONCOVALENT BINDING INTERACTIONS BETWEEN MOLECULES | HET NEDERLANDS KANKER INSTITUUT (NL) | 2017-05-25 | — | — | US | disclosed |
| US-20150246952-A1 | MEANS AND METHODS FOR BREAKING NONCOVALENT BINDING INTERACTIONS BETWEEN MOLECULES | HET NL KANKER INST (NL) | 2015-09-03 | — | — | US | disclosed |
| US-9079941-B2 | Means and methods for breaking noncovalent binding interactions between molecules | HET NEDERLANDS KANKER INSTITUUT (NL) | 2015-07-14 | — | — | US | disclosed |
| EP-1841791-B1 | MEANS AND METHODS FOR BREAKING NONCOVALENT BINDING INTERACTIONS BETWEEN MOLECULES | STICHTING NL KANKER INST (NL) | 2012-12-19 | — | — | EP | disclosed |
| US-20080145378-A1 | Means and Methods for Breaking Noncovalent Binding Interactions Between Molecules | HET NEDERLANDS KANKER INSTITUUT (NL) | 2008-06-19 | — | — | US | disclosed |
| EP-1841791-A2 | MEANS AND METHODS FOR BREAKING NONCOVALENT BINDING INTERACTIONS BETWEEN MOLECULES | Het Nederlands Kanker Instituut (NL) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006080837-A2 | MEANS AND METHODS FOR BREAKING NONCOVALENT BINDING INTERACTIONS BETWEEN MOLECULES | HET NEDERLANDS KANKER INSTITUUT (NL) | 2006-08-03 | — | — | WO | disclosed |
| EP-1683808-A1 | Means and methods for breaking noncovalent binding interactions between molecules | Het Nederlands Kanker Instituut (NL) | 2006-07-26 | — | — | EP | disclosed |