Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064992 | 0.73 | TNF (0.55) | CDK1KLK7TNFMKNK1CA12 | |
| SCHEMBL1203686 | 0.73 | MKNK1 (0.46) | CDK1KLK7CDK2TNFMKNK1 | |
| SCHEMBL19493137 | 0.69 | MKNK1 (0.42) | CDK1KLK7CDK2SMN1; SMN2MKNK1 | |
| SCHEMBL23768212 | 0.67 | MKNK1 (0.46) | CDK1KLK7MKNK1PDE4APDE4B | |
| SCHEMBL16831885 | 0.67 | SMN1; SMN2 (0.61) | GAASMN1; SMN2LMNACA12CA9 | |
| SCHEMBL4572217 | 0.66 | MKNK1 (0.49) | CDK1KLK7MKNK1PDE4APDE4B | |
| SCHEMBL31529438 | 0.66 | KLK7 (0.36) | KLK7MKNK1DYRK1A | |
| SCHEMBL432525 | 0.66 | TNF (0.61) | CDK2TNFDYRK1A | |
| SCHEMBL25420964 | 0.65 | ABL1 (0.36) | KLK7MKNK1DYRK1A | |
| SCHEMBL25420963 | 0.65 | ABL1 (0.36) | KLK7MKNK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | CBR3, CBR1, CYP4Z1 | CDK1 1483/4885KLK7 4679/4885CDK2 1820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.