Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16244584 | 0.95 | ALDH1A1 (0.58) | ALDH1A1CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL7371039 | 0.90 | ALDH1A1 (0.54) | ALDH1A1CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL315271 | 0.87 | ALDH1A1 (0.74) | ALDH1A1CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL2745809 | 0.87 | LMNA (0.52) | ALDH1A1CHRM5CHRM1CHRM3LMNA | |
| Ammonia Solution, Strong SCHEMBL10897945 | 0.84 | LMNA (0.50) | ALDH1A1CHRM5CHRM1CHRM3LMNA | |
| Ammonia Solution, Strong SCHEMBL9807764 | 0.84 | ALDH1A1 (0.70) | ALDH1A1CHRM5CHRM1CHRM3LMNA | |
| Acetic Acid SCHEMBL27535337 | 0.81 | ALDH1A1 (0.67) | ALDH1A1CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL2746597 | 0.81 | TSHR (0.52) | ALDH1A1CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL189930 | 0.81 | ALDH1A1 (0.74) | ALDH1A1CHRM5CHRM1CHRM3LMNA | |
| Acetic Acid Butyl Ester SCHEMBL3673349 | 0.81 | ALDH1A1 (0.72) | ALDH1A1CHRM5CHRM1CHRM3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080138295-A1 | Bechet's disease using cyclopropyl-N-carboxamide | CELGENE COPORATION | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138295-A1 | Bechet's disease using cyclopropyl-N-carboxamide | IL2, TNF, FGF2 | ALDH1A1 860/4885CHRM5 3391/4885CHRM1 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.