SCHEMBL4886443

SCHEMBL4886443

OC(Cn1ccnc1)C(O)(c1ccccc1)C1CCCC1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.45
CYP11B2 P19099 2/20 0.45
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
OGG1 O15527 1/20 0.42
AGER Q15109 1/20 0.41
CYP19A1 P11511 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31732800 0.77 OGG1 (0.59) CYP11B1CYP11B2MEN1KMT2AOGG1
SCHEMBL4889873 0.77 MEN1 (0.56) MEN1KMT2A
SCHEMBL4889718 0.76 KDM4E (0.47) MEN1KMT2AAGER
SCHEMBL4890266 0.76 MEN1 (0.58) MEN1KMT2A
SCHEMBL4881797 0.76 MEN1 (0.58) MEN1KMT2A
SCHEMBL4890692 0.74 SMN1; SMN2 (0.41) MEN1KMT2A
SCHEMBL4885076 0.74 MEN1 (0.54) MEN1KMT2A
SCHEMBL4889974 0.73 MEN1 (0.53) MEN1KMT2A
SCHEMBL4886108 0.73 KEAP1 (0.52) CYP11B1CYP11B2
SCHEMBL4889815 0.72 MEN1 (0.52) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080280883-A1 Muscarinic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2008-11-13 US claimed
US-20080280883-A1 Muscarinic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2008-11-13 US disclosed
EP-1794161-A2 MUSCARINIC RECEPTOR ANTAGONISTS Ranbaxy Laboratories Limited (IN) 2007-06-13 EP disclosed
WO-2006032994-A2 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2006-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280883-A1 Muscarinic Receptor Antagonists CHRM3, CHRM5, CHRM2 CYP11B1 486/4885CYP11B2 351/4885MEN1 1629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.