Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 9/20 | 0.52 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881110 | 0.90 | MAPKAPK2 (0.62) | MAPKAPK2ACKR3MCHR1DRD4SLC6A12 | |
| SCHEMBL4879370 | 0.88 | MAPKAPK2 (0.52) | MAPKAPK2ACKR3 | |
| Hydrochloric Acid SCHEMBL4895600 | 0.87 | MAPKAPK2 (0.51) | MAPKAPK2 | |
| SCHEMBL4880172 | 0.85 | MAPKAPK2 (0.49) | MAPKAPK2ACKR3CLK1GSK3BMAP3K14 | |
| SCHEMBL4889851 | 0.85 | MAPKAPK2 (0.49) | MAPKAPK2ACKR3CLK1GSK3BMAP3K14 | |
| SCHEMBL4883872 | 0.85 | MAPKAPK2 (0.49) | MAPKAPK2ACKR3MCHR1DRD4CLK1 | |
| SCHEMBL4887575 | 0.85 | MAPKAPK2 (0.51) | MAPKAPK2ACKR3MCHR1DRD4CLK1 | |
| Hydrochloric Acid SCHEMBL4887420 | 0.85 | MAPKAPK2 (0.56) | MAPKAPK2MCHR1DRD4 | |
| SCHEMBL4891195 | 0.84 | DRD4 (0.57) | MAPKAPK2MCHR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL4885713 | 0.84 | MAPKAPK2 (0.51) | MAPKAPK2ACKR3MCHR1DRD4CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | CCR1, CCL11, CXCR1 | MAPKAPK2 2482/4885ACKR3 16/4885POLB 4221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.