Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.52 |
| ▸ | SOS1 | Q07889 | 6/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4895600 | 0.99 | MAPKAPK2 (0.51) | MAPKAPK2SOS1BCHEACHEKRAS | |
| SCHEMBL4890287 | 0.90 | SOS1 (0.52) | MAPKAPK2SOS1BCHEACHEKRAS | |
| SCHEMBL4889967 | 0.89 | MAPKAPK2 (0.55) | MAPKAPK2SOS1BCHEACHEKRAS | |
| SCHEMBL4886641 | 0.88 | MAPKAPK2 (0.52) | MAPKAPK2ACKR3 | |
| SCHEMBL4881110 | 0.86 | MAPKAPK2 (0.62) | MAPKAPK2SIGMAR1ACKR3 | |
| SCHEMBL4893059 | 0.86 | SLC6A12 (0.53) | MAPKAPK2SOS1BCHEACHEKRAS | |
| SCHEMBL4890665 | 0.85 | SOS1 (0.50) | MAPKAPK2SOS1BCHEACHEKRAS | |
| SCHEMBL4887575 | 0.84 | MAPKAPK2 (0.51) | MAPKAPK2ACKR3 | |
| SCHEMBL4879391 | 0.82 | MAPKAPK2 (0.51) | MAPKAPK2ACKR3 | |
| SCHEMBL4886881 | 0.82 | MAPKAPK2 (0.49) | MAPKAPK2ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | disclosed |
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | disclosed |
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | CCR1, CCL11, CXCR1 | MAPKAPK2 2482/4885SOS1 2122/4885BCHE 2363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.