Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841806 | 1.00 | GSK3A (0.41) | GSK3AGSK3BMAT2AJAK2JAK1 | |
| SCHEMBL11841518 | 1.00 | GSK3A (0.41) | GSK3AGSK3BMAT2AJAK2JAK1 | |
| Hexazinone SCHEMBL66377 | 1.00 | GSK3A (0.41) | GSK3AGSK3BMAT2AJAK2JAK1 | |
| SCHEMBL11523573 | 0.98 | GSK3A (0.39) | GSK3AGSK3BMAT2AJAK2JAK1 | |
| SCHEMBL11843893 | 0.95 | MAT2A (0.38) | GSK3AGSK3BMAT2AJAK2JAK1 | |
| Hexazinone SCHEMBL11445646 | 0.93 | GSK3A (0.37) | GSK3AGSK3BMAT2AJAK2JAK1 | |
| Hexazinone SCHEMBL11625731 | 0.87 | MAT2A (0.36) | GSK3AGSK3BMAT2AJAK2JAK1 | |
| SCHEMBL11841234 | 0.86 | MAT2A (0.39) | MAT2AADORA2APRKDCALOX15PIK3CA | |
| SCHEMBL11851964 | 0.85 | GSK3A (0.38) | GSK3AGSK3BJAK2JAK1JAK3 | |
| SCHEMBL11851040 | 0.85 | MAT2A (0.41) | MAT2APRKDCPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3906245-B1 | MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS | DOW SILICONES CORP (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-3645640-B1 | SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME | DOW SILICONES CORP (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11807775-B2 | Silicone-organic copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| US-11760841-B2 | Silicone-polycarbonate copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3898779-B1 | SILICONE-POLYESTER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORP (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-3898781-B1 | SILICONE-POLYCARBONATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORP (US) | 2023-01-04 | — | — | EP | disclosed |
| CN-113272362-B | Silicone-polyester copolymers, sealants including silicone-polyester copolymers, and related methods | 美国陶氏有机硅公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-110997757-B | Isocyanate-functional silicone-polyether copolymers, silicone-polyether-urethane copolymers formed therewith, sealants including the same, and related methods | 美国陶氏有机硅公司 | 2022-03-08 | — | — | CN | disclosed |
| US-20220064482-A1 | SILICONE-ORGANIC COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORPORATION | 2022-03-03 | — | — | US | disclosed |
| US-20220064383-A1 | SILICONE-POLYACRYLATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORPORATION | 2022-03-03 | — | — | US | disclosed |
| WO-2012134788-A1 | COMPOSITIONS CONTAINING PHOSPHATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012134786-A1 | COMPOSITIONS CONTINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2012-10-04 | — | — | WO | disclosed |
| US-20080118734-A1 | Coating Compositions | DOW CORNING IRELAND LTD. (IE) | 2008-05-22 | — | — | US | disclosed |
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0546082-A1 | HERBICIDAL PYRROLESULFONYLUREAS. | DU PONT (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992004827-A1 | HERBICIDAL SUBSTITUTED BICYCLIC TRIAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-02 | — | — | WO | disclosed |
| EP-0184039-B1 | LIQUID BIOLOGICALLY ACTIVE COMPOSITIONS | MELAMINE CHEMICALS, INC. (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0184039-A1 | Liquid biologically active compositions | MELAMINE CHEMICALS, INC. (US) | 1986-06-11 | — | — | EP | disclosed |