Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.35 |
| ▸ | PRKDC | P78527 | 10/20 | 0.35 |
| ▸ | MTOR | P42345 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexazinone SCHEMBL66377 | 0.98 | GSK3A (0.41) | GSK3AGSK3BMAT2APIK3CAPRKDC | |
| SCHEMBL11841806 | 0.98 | GSK3A (0.41) | GSK3AGSK3BMAT2APIK3CAPRKDC | |
| SCHEMBL11841518 | 0.98 | GSK3A (0.41) | GSK3AGSK3BMAT2APIK3CAPRKDC | |
| Hexazinone SCHEMBL4887146 | 0.98 | GSK3A (0.41) | GSK3AGSK3BMAT2APIK3CAPRKDC | |
| SCHEMBL11843893 | 0.97 | MAT2A (0.38) | GSK3AGSK3BMAT2APIK3CAPRKDC | |
| Hexazinone SCHEMBL11445646 | 0.92 | GSK3A (0.37) | GSK3AGSK3BMAT2APIK3CAPRKDC | |
| SCHEMBL11841234 | 0.88 | MAT2A (0.39) | MAT2APIK3CAPRKDCMTORADORA2A | |
| SCHEMBL11851040 | 0.86 | MAT2A (0.41) | MAT2APIK3CAPRKDCMTOR | |
| Hexazinone SCHEMBL11625731 | 0.86 | MAT2A (0.36) | GSK3AGSK3BMAT2APIK3CAPRKDC | |
| SCHEMBL11845271 | 0.86 | JAK2 (0.34) | MAT2AJAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3983116-A | Herbicidal triazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-09-28 | — | — | US | claimed |
| US-4178448-A | Process for preparing herbicidal triazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4150225-A | CYCLIZATION OF ALKYL N-/N-SUBSTITUTED CARBAMOYL-N,N'-DIALKYLAMIDINO/-N-METHYLCARBAMATE, REMOVAL OF ALCOHOL BY-PRODUCT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| US-3983116-A | Herbicidal triazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-09-28 | — | — | US | disclosed |