SCHEMBL4887355

SCHEMBL4887355

O=C(O)CC=C(CC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
KDM4E B2RXH2 1/20 0.54
CPB1 P15086 1/20 0.53
ALOX15 P16050 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP2D6 P10635 1/20 0.41
LDHA P00338 1/20 0.40
SRR Q9GZT4 1/20 0.40
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.34
ABAT P80404 1/20 0.34
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13541377 1.00 TSHR (0.54) TSHRKDM4ECPB1ALOX15ALDH1A1
SCHEMBL19407227 1.00 TSHR (0.54) TSHRKDM4ECPB1ALOX15ALDH1A1
SCHEMBL9751771 0.80 CPB1 (0.46) TSHRKDM4ECPB1ALOX15ALDH1A1
SCHEMBL9751768 0.80 CPB1 (0.46) TSHRKDM4ECPB1ALOX15ALDH1A1
SCHEMBL1674910 0.79 TSHR (0.54) TSHRKDM4ECPB1ALOX15LDHA
SCHEMBL10663575 0.78 EGLN1 (0.41) TSHRKDM4ECPB1ALOX15ALDH1A1
SCHEMBL542017 0.77 LMNA (0.45) TSHRKDM4ECPB1ALOX15ALDH1A1
SCHEMBL8604104 0.77 FFAR3 (0.43) TSHRKDM4ECPB1ALOX15ALDH1A1
SCHEMBL542016 0.77 LMNA (0.45) TSHRKDM4ECPB1ALOX15ALDH1A1
SCHEMBL216018 0.77 TSHR (0.52) TSHRKDM4ECPB1ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0578450-B1 Process for preparing polysuccinimides from maleamic acid ROHM & HAAS (US) 1998-01-14 EP claimed
EP-0578451-B1 Process for preparing polysuccinimide polymers ROHM & HAAS (US) 1998-01-14 EP claimed
CN-1036927-C Polysuccinimide polymers and process for preparing polysuccinimide polymers ROHM & HAAS (US) 1998-01-07 CN claimed
US-5463017-A Process for preparing polysuccinimides from maleamic acid ROHM AND HAAS COMPANY (US) 1995-10-31 US claimed
US-5371179-A Polysuccinimide polymers and process for preparing polysuccinimide polymers ROHM AND HAAS COMPANY (US) 1994-12-06 US claimed
US-5371177-A Process for preparing polysuccinimides from maleamic acid ROHM AND HAAS COMPANY (US) 1994-12-06 US claimed
CN-1081449-A Polysuccinimide and method for making thereof ROHM & HAAS (US) 1994-02-02 CN claimed
EP-0578451-A2 Polysuccinimide polymers and process for preparing polysuccinimide polymers ROHM AND HAAS COMPANY (US) 1994-01-12 EP claimed
EP-0578450-A2 Process for preparing polysuccinimides from maleamic acid ROHM AND HAAS COMPANY (US) 1994-01-12 EP claimed
CN-117062880-A Antifouling coating composition 日东化成株式会社 2023-11-14 CN disclosed
US-20080164050-A1 Regular Square Insulating Cable, Application of Such Regular Square Insulating Cable and Method for Manufacturing Such Regular Square Insulating Cable MITSUBISHI CABLE INDUSTRIES, LTD. (JP) 2008-07-10 US disclosed
EP-1858030-A1 REGULAR SQUARE INSULATING CABLE, APPLICATION OF SUCH REGULAR SQUARE INSULATING CABLE AND METHOD FOR MANUFACTURING SUCH REGULAR SQUARE INSULATING CABLE Mitsubishi Cable Industries, Ltd. (JP) 2007-11-21 EP disclosed
EP-0578450-B1 Process for preparing polysuccinimides from maleamic acid ROHM & HAAS (US) 1998-01-14 EP disclosed
EP-0578451-B1 Process for preparing polysuccinimide polymers ROHM & HAAS (US) 1998-01-14 EP disclosed
US-5463017-A Process for preparing polysuccinimides from maleamic acid ROHM AND HAAS COMPANY (US) 1995-10-31 US disclosed
US-5371179-A Polysuccinimide polymers and process for preparing polysuccinimide polymers ROHM AND HAAS COMPANY (US) 1994-12-06 US disclosed
US-5371177-A Process for preparing polysuccinimides from maleamic acid ROHM AND HAAS COMPANY (US) 1994-12-06 US disclosed
EP-0578451-A2 Polysuccinimide polymers and process for preparing polysuccinimide polymers ROHM AND HAAS COMPANY (US) 1994-01-12 EP disclosed
EP-0578450-A2 Process for preparing polysuccinimides from maleamic acid ROHM AND HAAS COMPANY (US) 1994-01-12 EP disclosed