Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881148 | 0.82 | MAPT (0.36) | GAAMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL4881153 | 0.79 | MAPT (0.34) | GAAMAPTHPGDL3MBTL1KDM4E | |
| SCHEMBL3874836 | 0.78 | KDM4E (0.47) | GAAMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL3882623 | 0.75 | NQO1 (0.43) | GAAMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL3882591 | 0.75 | RECQL (0.50) | GAAMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL4887783 | 0.74 | IGF1R (0.38) | GAAMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL3878088 | 0.73 | ALDH1A1 (0.52) | GAAMAPTHPGDALDH1A1KDM4E | |
| SCHEMBL3877504 | 0.73 | KDM4E (0.47) | GAAMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL3881350 | 0.73 | MAOA (0.48) | GAAMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL3873224 | 0.72 | NQO1 (0.43) | GAAMAPTHPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | disclosed |