Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.59 |
| ▸ | CA2 | P00918 | 12/20 | 0.59 |
| ▸ | CA9 | Q16790 | 12/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 7/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488760 | 0.87 | CA1 (0.57) | CA1CA2CA9CA12CA3 | |
| SCHEMBL488684 | 0.85 | CA1 (0.42) | CA1CA2CA9CA12CA3 | |
| SCHEMBL12707453 | 0.85 | CA1 (0.64) | CA1CA2CA9CA12CA3 | |
| SCHEMBL24133598 | 0.83 | CA1 (0.69) | CA1CA2CA9CA12CA3 | |
| SCHEMBL28512125 | 0.82 | CA1 (0.61) | CA1CA2CA9CA12CA3 | |
| SCHEMBL15957129 | 0.81 | CA1 (0.39) | CA1CA2CA9CA12CA3 | |
| SCHEMBL23112919 | 0.81 | CA1 (0.50) | CA1CA2CA9CA12CA3 | |
| SCHEMBL15091821 | 0.80 | CA1 (0.42) | CA1CA2CA9CA12CA3 | |
| SCHEMBL23281878 | 0.79 | CA1 (0.57) | CA1CA2CA9CA12CA3 | |
| SCHEMBL2415277 | 0.79 | CA1 (0.68) | CA1CA2CA9CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106197-B2 | Aminoheteroaryl compounds as protein kinase inhibitors | PFIZER INC. (US) | 2012-01-31 | — | — | US | disclosed |