SCHEMBL4888846

SCHEMBL4888846

C=CC(=O)OCCCCSC

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.67
ALDH1A1 P00352 4/20 0.67
CYP3A4 P08684 2/20 0.67
HPGD P15428 1/20 0.60
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.42
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 3/20 0.38
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PTGS2 P35354 1/20 0.32
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NAAA Q02083 1/20 0.31
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4774300 0.94 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL4776683 0.87 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2828789 0.86
SCHEMBL28541902 0.84 TSHR (0.72) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL244114 0.83 TSHR (0.95) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL30194945 0.82 TSHR (0.76) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21246644 0.82 TSHR (0.76) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2721058 0.81 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17372990 0.81 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
Ethylene SCHEMBL977945 0.81 TSHR (0.90) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018017570-A1 A HAIR STRAIGHTENING AND STYLING COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO claimed
US-8648160-B2 Optical semiconductor sealing material IDEMITSU KOSAN CO., LTD. (JP) 2014-02-11 US claimed
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 US disclosed
CN-118359523-B Acrylic monomer and application thereof in photo-curing functional coating 广东博兴新材料科技股份有限公司 2024-12-17 CN disclosed
CN-118359523-A Acrylic monomer and application thereof in photo-curing functional coating 广东博兴新材料科技股份有限公司 2024-07-19 CN disclosed
CN-117185973-A Acrylic monomer and application thereof in photo-curing functional coating 广东博兴新材料科技股份有限公司 2023-12-08 CN disclosed
WO-2023102600-A1 SYNTHESIS OF AMPHIPHILIC BLOCK COPOLYMERS AND POLYMERIC NANOFIBERS PRODUCED THEREFROM NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2023-06-15 WO disclosed
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2019-12-19 US disclosed
WO-2018132548-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-19 WO disclosed
WO-2018017570-A1 A HAIR STRAIGHTENING AND STYLING COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO disclosed
US-8648160-B2 Optical semiconductor sealing material IDEMITSU KOSAN CO., LTD. (JP) 2014-02-11 US disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed
US-6491903-B1 NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY WASHINGTON UNIVERSITY 2002-12-10 US disclosed
US-6383500-B1 Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications WASHINGTON UNIVERSITY 2002-05-07 US disclosed
EP-0802067-B1 DIRECT DRAWING TYPE WATERLESS PLANOGRAPHIC ORIGINAL FORM PLATE TORAY INDUSTRIES (JP) 2002-04-24 EP disclosed
US-6096476-A DIRECTLY IMAGEABLE RAW PLATE HAVING A HEAT INSULATING LAYER, HEAT SENSITIVE LAYER COMPRISING A LIGHT TO HEAT CONVERTING MATERIAL AND INK REPLELLENT LAYER IN THIS ORDER ON SUBSTRATE; PLATE HAS SPECIFIED ELASTIC MODULUS AND TENSILE PROPERTIES TORAY INDUSTRIES, INC. (JP) 2000-08-01 US disclosed
EP-0678785-B1 DRY LITHOGRAPHIC PLATE TORAY INDUSTRIES (JP) 2000-05-10 EP disclosed
US-5866294-A HIGH DURABLE PRINTING TORAY INDUSTRIES, INC. (JP) 1999-02-02 US disclosed
EP-0802067-A1 DIRECT DRAWING TYPE WATERLESS PLANOGRAPHIC ORIGINAL FORM PLATE TORAY INDUSTRIES, INC. (JP) 1997-10-22 EP disclosed
EP-0678785-A1 DRY LITHOGRAPHIC FORME TORAY INDUSTRIES, INC. (JP) 1995-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ADSL, ABHD6, APH1B TSHR 4275/4885ALDH1A1 2283/4885CYP3A4 3142/4885
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF PCNA, ADSL, APH1B TSHR 3587/4885ALDH1A1 2371/4885CYP3A4 3590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.