Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19511846 | 0.81 | TSHR (0.43) | LMNATSHRMETAP1THRBALDH1A1 | |
| SCHEMBL1554454 | 0.80 | LMNA (0.56) | LMNATSHRMETAP1THRBALDH1A1 | |
| SCHEMBL3921436 | 0.80 | LMNA (0.62) | LMNATSHRMETAP1THRBALDH1A1 | |
| SCHEMBL8901993 | 0.78 | LMNA (0.43) | LMNATSHRTHRBALDH1A1 | |
| SCHEMBL17715618 | 0.77 | TSHR (0.42) | LMNATSHRMETAP1THRBALDH1A1 | |
| SCHEMBL14730127 | 0.77 | LMNA (0.46) | LMNATSHRMETAP1 | |
| SCHEMBL2335709 | 0.76 | LMNA (0.50) | LMNATSHRMETAP1THRBALDH1A1 | |
| SCHEMBL15800763 | 0.75 | LMNA (0.42) | LMNATSHRTHRBALDH1A1 | |
| SCHEMBL9506729 | 0.75 | LMNA (0.42) | LMNATSHRTHRBALDH1A1 | |
| SCHEMBL17951325 | 0.75 | LMNA (0.42) | LMNATSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293880-A1 | Liquid, Thermally Curable Mixtures, Their Preparation and Use | BASF COATINGS AG (DE) | 2008-11-27 | — | — | US | claimed |