Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30139979 | 1.00 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL30050771 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL10944497 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL11392451 | 0.84 | HDAC6 (0.47) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL28505268 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL29662040 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL4889521 | 0.77 | TSHR (0.57) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL3474082 | 0.77 | POLB (0.46) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL31228793 | 0.77 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL5793121 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008508314-A | — | — | 2008-03-21 | — | — | JP | claimed |
| EP-1778242-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | IRM LLC (BM) | 2007-05-02 | — | — | EP | claimed |
| WO-2006015259-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | IRM LLC (BM) | 2006-02-09 | — | — | WO | claimed |