Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214354 | 0.81 | ALDH1A1 (0.48) | TSHRALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL30139979 | 0.77 | ALDH1A1 (0.55) | TSHRALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL4889518 | 0.77 | ALDH1A1 (0.55) | TSHRALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL10944497 | 0.76 | ALDH1A1 (0.53) | TSHRALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL30050771 | 0.76 | ALDH1A1 (0.53) | TSHRALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL27150961 | 0.75 | ALDH1A1 (0.47) | TSHRALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL15605424 | 0.73 | TSHR (1.00) | TSHRALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL29580418 | 0.72 | KDM4E (0.51) | TSHRALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL6390410 | 0.72 | KDM4E (0.51) | TSHRALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL23709224 | 0.71 | HTR7 (0.55) | TSHRALDH1A1LMNAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008508314-A | — | — | 2008-03-21 | — | — | JP | claimed |
| EP-1778242-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | IRM LLC (BM) | 2007-05-02 | — | — | EP | claimed |
| WO-2006015259-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | IRM LLC (BM) | 2006-02-09 | — | — | WO | claimed |