SCHEMBL4889531

SCHEMBL4889531

C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.56
MEN1 O00255 1/20 0.55
TTR P02766 1/20 0.55
PPOX P50336 1/20 0.55
KMT2A Q03164 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
THRB P10828 1/20 0.47
MRGPRX4 Q96LA9 7/20 0.46
HTR2A P28223 2/20 0.46
SLC6A4 P31645 2/20 0.46
KCNH2 Q12809 2/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.42
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39100 1.00 FFAR1 (0.56) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL2681468 1.00 FFAR1 (0.56) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL15844933 1.00 FFAR1 (0.56) FFAR1MEN1TTRPPOXKMT2A
Clopyralid SCHEMBL7579616 0.92 MEN1 (0.50) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL11260796 0.90 MEN1 (0.55) FFAR1MEN1TTRPPOXKMT2A
Mecoprop SCHEMBL7587205 0.90 TSHR (0.53) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9838509 0.89 TDP1 (0.51) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9838520 0.89 TDP1 (0.51) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9839768 0.89 TDP1 (0.51) FFAR1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL7589284 0.89 TDP1 (0.76) FFAR1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746505-B1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW SILICONES CORP (US) 2024-06-26 EP disclosed
EP-3906245-B1 MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS DOW SILICONES CORP (US) 2024-05-29 EP disclosed
US-20240124709-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW GLOBAL TECHNOLOGIES LLC 2024-04-18 US disclosed
EP-3645640-B1 SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME DOW SILICONES CORP (US) 2024-03-06 EP disclosed
US-11884821-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2024-01-30 US disclosed
WO-2023215360-A1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORPORATION (US) 2023-11-09 WO disclosed
US-11807775-B2 Silicone-organic copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-11-07 US disclosed
US-11760841-B2 Silicone-polycarbonate copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-09-19 US disclosed
EP-3898779-B1 SILICONE-POLYESTER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2023-02-08 EP disclosed
EP-3898781-B1 SILICONE-POLYCARBONATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2023-01-04 EP disclosed
US-20140200348-A1 Vanadium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts DOW CORNING CORPORATION (US) 2014-07-17 US disclosed
US-20140194627-A1 Zinc Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts DOW CORNING CORPORATION 2014-07-10 US disclosed
US-20140183398-A1 Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2014-07-03 US disclosed
US-20140187783-A1 Hafnium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts DOW CORNING CORPORATION 2014-07-03 US disclosed
US-20140171547-A1 Bismuth Containing Complex and Condensation Reaction Curable Compositions and Methods for the Preparation and Use of the Compositions DOW CORNING CORPORATION 2014-06-19 US disclosed
US-20140135517-A1 Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use DOW CORNING CORPORATION (US) 2014-05-15 US disclosed
US-20140100347-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2014-04-10 US disclosed
US-20140039089-A1 Compositions Containing Phosphonate Catalysts And Methods For The Preparation And Use Of The Compositions DOW CORNING CORPORATION (US) 2014-02-06 US disclosed
US-20140018467-A1 COMPOSITIONS CONTAINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2014-01-16 US disclosed
US-20080118734-A1 Coating Compositions DOW CORNING IRELAND LTD. (IE) 2008-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140135517-A1 Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use HIRA, HIRIP3, CROCC FFAR1 3199/4885MEN1 1410/4885TTR 2891/4885
US-20140183398-A1 Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts HIRA, ALG8, CAD FFAR1 4212/4885MEN1 832/4885TTR 3256/4885
US-20140200348-A1 Vanadium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts VCL, ALG8, VMA21 FFAR1 4123/4885MEN1 2636/4885TTR 1519/4885
US-20140194627-A1 Zinc Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts ZRANB2, ZKSCAN2, SLC39A3 FFAR1 4035/4885MEN1 2731/4885TTR 2541/4885
US-20140187783-A1 Hafnium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts HIRA, HACL2, CROCC FFAR1 3752/4885MEN1 2255/4885TTR 3079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.