Clopyralid

Clopyralid

SCHEMBL7579616

C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.O=C(O)c1nc(Cl)ccc1Cl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
TTR P02766 1/20 0.50
PPOX P50336 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
FFAR1 O14842 5/20 0.48
MRGPRX4 Q96LA9 6/20 0.42
LMNA P02545 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
THRB P10828 1/20 0.41
HTR2A P28223 2/20 0.40
SLC6A4 P31645 2/20 0.40
KCNH2 Q12809 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2681468 0.92 FFAR1 (0.56) MEN1TTRPPOXKMT2ATDP1
SCHEMBL15844933 0.92 FFAR1 (0.56) MEN1TTRPPOXKMT2ATDP1
SCHEMBL39100 0.92 FFAR1 (0.56) MEN1TTRPPOXKMT2ATDP1
SCHEMBL4889531 0.92 FFAR1 (0.56) MEN1TTRPPOXKMT2ATDP1
Acifluorfen SCHEMBL7589284 0.83 TDP1 (0.76) MEN1TTRPPOXKMT2ATDP1
Simazine SCHEMBL7586016 0.83 FFAR1 (0.46) MEN1TTRPPOXKMT2ATDP1
Quinmerac SCHEMBL7588187 0.83 MEN1 (0.46) MEN1TTRPPOXKMT2ATDP1
SCHEMBL11260796 0.82 MEN1 (0.55) MEN1TTRPPOXKMT2ATDP1
Mecoprop SCHEMBL7587205 0.82 TSHR (0.53) MEN1TTRPPOXKMT2ATDP1
Lactofen SCHEMBL7578105 0.82 TDP1 (0.60) MEN1TTRPPOXKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885TTR 1945/4885PPOX 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.