Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TYMS | P04818 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026846 | 0.82 | NPSR1 (0.57) | CFTRGOPCTDP1MEN1KMT2A | |
| SCHEMBL1025601 | 0.81 | CFTR (0.52) | CFTRGOPCTDP1MEN1KMT2A | |
| SCHEMBL4020684 | 0.81 | POLB (0.50) | TDP1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL18161910 | 0.78 | CFTR (0.59) | CFTRGOPCTDP1MEN1KMT2A | |
| SCHEMBL220741 | 0.77 | CFTR (0.55) | CFTRGOPCTDP1MEN1KMT2A | |
| SCHEMBL5146765 | 0.77 | KDM4E (0.47) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL5146662 | 0.77 | KDM4E (0.47) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL5148245 | 0.77 | KDM4E (0.47) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL1882657 | 0.77 | KMT2A (0.42) | TDP1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL25005560 | 0.76 | CFTR (0.54) | CFTRGOPCTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080241943-A1 | Subnanomolar Precipitator of Thiophilic Metals | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-10-02 | — | — | US | disclosed |
| WO-2006055883-A2 | SUBNANOMOLAR PRECIPITATOR OF THIOPHILIC METALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241943-A1 | Subnanomolar Precipitator of Thiophilic Metals | LGALS2, LGALS4, CA2 | CFTR 4729/4885GOPC 468/4885TDP1 2850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.