LGALS4 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1521368	0.52	4/20
SCHEMBL1682156	0.52	4/20
SCHEMBL1682180	0.52	4/20
SCHEMBL411273	0.77	3/20
SCHEMBL411274	0.77	3/20
SCHEMBL411624	0.77	3/20
SCHEMBL411625	0.77	3/20
SCHEMBL736151	0.77	3/20
SCHEMBL416471	0.72	3/20
SCHEMBL2190560	0.68	3/20
SCHEMBL754690	0.67	3/20
SCHEMBL754691	0.67	3/20
SCHEMBL769002	0.62	3/20
SCHEMBL887972	0.62	3/20
SCHEMBL887984	0.62	3/20
SCHEMBL889532	0.62	3/20
SCHEMBL889573	0.62	3/20
SCHEMBL890313	0.62	3/20
SCHEMBL411272	0.61	3/20
SCHEMBL411623	0.61	3/20

Clinical trials — most relevant to LGALS4 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Study of Sacubitril/ValsarTan on MyocardIal OxygenatioN and Fibrosis in Heart Failure With Preserved Ejection Fraction	PHASE3	WITHDRAWN
A Phase 2 Extension of Study GCS-100-CS-4003	PHASE2	WITHDRAWN
A Phase 2b Study of GCS-100 in Patients With Chronic Kidney Disease Caused by Diabetes	PHASE2	UNKNOWN
A Phase 2a Study of Weekly Doses of GCS-100 in Patients With Chronic Kidney Disease	PHASE2	COMPLETED
Vitamin D Deficiency Treatment Outcomes After Non-ST-Segment Elevation Myocardial Infarction	PHASE2	UNKNOWN
Effect of Modified Citrus Pectin on PSA Kinetics in Biochemical Relapsed PC With Serial Increases in PSA	PHASE2	COMPLETED
A Phase 2 Extension Study of Study GCS-100-CS-4002	PHASE2	COMPLETED
GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer Patients	PHASE1	COMPLETED
The Diagnostic Value of Serum Oncostatin M and Galactin 3 as Biomarkers in Diagnosis of Ulcerative Colitis Disease	nan	NOT_YET_RECRUITING
A Wearable Device and AI-Supported Diet and Exercise Intervention	nan	RECRUITING
Urinary G3BP as a Novel Biomarker in Lupus Nephritis	nan	NOT_YET_RECRUITING
A Serum Galectin-3 Levels in Placenta Accreta Spectrum Pregnancies	nan	COMPLETED
The Role of Galectins in the Non-invasive Diagnosis of Endometriosis	nan	UNKNOWN
Galectin and Respiratory Weaning	nan	UNKNOWN
Testicular Proteins for Sperm Retrieval Prediction Protein1, Testis-Expressed Gene 101, and Lectin Galactoside-binding Protein in Predicting Surgical Sperm Retrieval in Men With Non-Obstructive Azoospermia	nan	UNKNOWN
Galectin-3 Binding Protein in Cardiovascular Disease and Chronic Heart Failure	nan	COMPLETED
Effect of Low-Glycemic Index Mediterranean Diet on AGEs	nan	COMPLETED
Galectin-3 for Thromboembolic Formation in Patients With Atrial Fibrillation CHA₂DS₂-VASc Scoring	nan	UNKNOWN
Galectin-3 in Septic and Non-septic Acute Kidney Injury	nan	UNKNOWN
Galectin 3 Dosage in Diagnosis of Nodular and Multinodular Goiter	nan	COMPLETED
Galectin-3 as a Biomarker in Patients With Chagas Disease	nan	COMPLETED
Evaluation of Serum Galectin-9 Level in Systemic Lupus Erythematosus Patients and it's Association With Disease Activity and Organ Damage	nan	UNKNOWN
Blood Collection From Heart Failure Patients to Evaluate for Galectin-3 Measurement Differences Using Various Collection Tubes	nan	COMPLETED
Serum Galectin-3 as a Marker of Human Papillomavirus Infection	nan	COMPLETED
Evaluation of Galectin-3 in Serum and Saliva of Pemphigus Patients	nan	UNKNOWN
Biomarkers for Risk Stratification After STEMI	nan	UNKNOWN
Galectin-3 in Patients With Endometriosis	nan	UNKNOWN
Fontan Imaging Biomarkers (FIB) Study	nan	COMPLETED
Glycoprotein and Glycan in Tissue and Blood Samples of Patients With Stage IB-IVA Cervical Cancer Undergoing Surgery to Remove Pelvic and Abdominal Lymph Nodes	nan	COMPLETED
Correlational Study on the Biomarkers Application to the Prediction and Diagnosis of Cardiovascular Diseases	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a LGALS4 binder may also engage these)

Protein	Name	Similarity
Q29058	—	0.999	Q29058 →
P38552	—	0.998	P38552 →
O54891	—	0.997	O54891 →
Q8K419	—	0.993	Q8K419 →
Q3T0D6	—	0.992	Q3T0D6 →
P97840	—	0.986	P97840 →
O08573	—	0.984	O08573 →
Q6DKI2	—	0.981	Q6DKI2 →
LGALS9	Galectin-9	0.978	landscape →
Q3MHZ8	—	0.978	Q3MHZ8 →
Q3B8N2	—	0.978	Q3B8N2 →
P07583	—	0.974	P07583 →
P47967	—	0.972	P47967 →
P47845	—	0.970	P47845 →
Q62665	—	0.970	Q62665 →
LGALS3	Galectin-3	0.967	landscape →
P97590	—	0.967	P97590 →
Q9JL15	—	0.967	Q9JL15 →
P47953	—	0.966	P47953 →
LGALS8	Galectin-8	0.965	landscape →
O44126	—	0.965	O44126 →
P11762	—	0.964	P11762 →
P36573	—	0.963	P36573 →
Q05315	—	0.961	Q05315 →
Q09581	—	0.959	Q09581 →
Q5R7M1	—	0.959	Q5R7M1 →
P16110	—	0.959	P16110 →
Q9Z144	—	0.959	Q9Z144 →
C0HJR3	—	0.958	C0HJR3 →
P08699	—	0.955	P08699 →