SCHEMBL4890028

SCHEMBL4890028

CCCCC(CC)COCCC1(CC)COC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.50
ALDH1A1 P00352 5/20 0.47
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP14 P50281 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
TSHR P16473 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
ATM Q13315 1/20 0.36
CA2 P00918 1/20 0.32
NCOA1 Q15788 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
RECQL P46063 1/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
CHRM1 P11229 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124322 0.85 ALDH1A1 (0.49) CYP3A4ALDH1A1MMP9MMP8MMP14
SCHEMBL12163403 0.81 ALDH1A1 (0.39) CYP3A4ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL1377568 0.81 ALDH1A1 (0.39) CYP3A4ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL19105133 0.79 ALDH1A1 (0.43) CYP3A4ALDH1A1MMP9MMP8MMP14
SCHEMBL27785670 0.77 ALDH1A1 (0.44) CYP3A4ALDH1A1MMP9MMP8MMP14
SCHEMBL4204484 0.76 ALDH1A1 (0.41) CYP3A4ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL6446139 0.75 ALDH1A1 (0.43) CYP3A4ALDH1A1MMP9MMP8MMP14
SCHEMBL1835296 0.75 CYP3A4 (0.74) CYP3A4ALDH1A1MMP9MMP8MMP14
SCHEMBL27513820 0.75 EPHX1 (0.32)
SCHEMBL31730325 0.74 HTT (0.41) ALDH1A1TDP1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080044149-A1 Polymerizable Composition TOYO INK MFG. CO., LTD. (JP) 2008-02-21 US disclosed
EP-1516015-A1 LOW ACIDITY PHOSPHATE ESTERS Akzo Nobel N.V. (NL) 2005-03-23 EP disclosed
WO-2004000922-A1 LOW ACIDITY PHOSPHATE ESTERS AKZO NOBEL N.V. (NL) 2003-12-31 WO disclosed